Evaluating eight indicators for identifying metabolic syndrome in Chinese and American adolescents

被引:0
|
作者
Hu, Xuan [1 ]
Yang, Zhuoqiao [1 ]
Ge, Wenxin [2 ]
Ding, Yaling [1 ]
Zhong, Yi [1 ]
Long, Jianing [1 ]
Zhu, Xiaoyan [3 ]
Hu, Jia [3 ]
Yin, Jieyun [1 ,4 ]
机构
[1] Soochow Univ, Med Coll, Dept Epidemiol & Hlth Stat, Suzhou, Jiangsu, Peoples R China
[2] Sun Yat Sen Univ, Sch Publ Hlth, Dept Maternal & Child Hlth, Guangzhou, Peoples R China
[3] Suzhou Ctr Dis Prevent & Control, Suzhou, Jiangsu, Peoples R China
[4] Jiangsu Key Lab Prevent & Translat Med Major Chron, Suzhou, Jiangsu, Peoples R China
关键词
BODY-MASS INDEX; NUTRITION EXAMINATION SURVEY; CARDIOMETABOLIC RISK; WAIST CIRCUMFERENCE; NATIONAL-HEALTH; CHILDREN; OBESITY; FAT; PREVALENCE; BURDEN;
D O I
10.1038/s41390-024-03247-8
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
BackgroundEarly intervention and diagnosis of Metabolic Syndrome (MetS) are crucial for preventing adult cardiovascular disease. However, the optimal indicator for identifying MetS in adolescent remains controversial.MethodsIn total,1408 Chinese adolescents and 3550 American adolescents aged 12-17 years were included. MetS was defined according to the modified version for adolescents based on Adult Treatment Panel III (NCEP-ATP III) criteria. Areas under the curve (AUC) and corresponding 95% confidence interval (95% CI) of 8 anthropometric/metabolic indexes, such as waist circumference (WC), body mass index (BMI), a body shape index (ABSI), waist triglyceride index (WTI), were calculated to illustrate their ability to differentiate MetS. Sensitivity analysis using the other MetS criteria was performed.ResultsUnder the modified NCEP-ATP III criteria, WTI had the best discriminating ability in overall adolescents, with AUC of 0.922 (95% CI: 0.900-0.945) in Chinese and 0.959 (95% CI: 0.949-0.969) in American. In contrast, ABSI had the lowest AUCs. Results of sensitivity analysis were generally consistent for the whole Chinese and American population, with the AUC for WC being the highest under some criteria, but it was not statistically different from that of WTI.ConclusionsWTI had relatively high discriminatory power for MetS detection in Chinese and American adolescents, but the performance of ABSI was poor.ImpactWhile many studies have compared the discriminatory power of some anthropometric indicators for MetS, there are few focused on pediatrics.The current study is the first to compare the discriminating ability of anthropometric/metabolic indicators (WC, BMI, TMI, ABSI, WHtR, VAI, WTI, and TyG) for MetS in adolescents.WTI remains the optimal indicator in screening for MetS in adolescents.WC was also a simple and reliable indicator when screening for MetS in adolescents, but the performance of ABSI was poor.This study provides a theoretical basis for the early identification of MetS in adolescents by adopting effective indicators.
引用
收藏
页码:1355 / 1363
页数:9
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