The Relentless Recurrence of Diffuse Alveolar Hemorrhage in Catastrophic Antiphospholipid Syndrome and Lupus: A Therapeutic Challenge

被引：0

作者：

Rahman, Aruni ^{[1
]}

Nathani, Mashal ^{[2
]}

Malekan, Michael ^{[3
]}

机构：

[1] New York Presbyterian Brooklyn Methodist Hosp, Internal Med, Brooklyn, NY 11215 USA

[2] Med Univ Amer, Internal Med, Charlestown, St Kitts & Nevi

[3] New York Presbyterian Brooklyn Methodist Hosp, Rheumatol, Brooklyn, NY USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 06期

关键词：

bleeding; pulmonary hemorrhage; alveolar hemorrhage; systemic lupus erythematosus antiphospholipid; antibodies; catastrophic antiphospholipid syndrome;

D O I：

10.7759/cureus.62635

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diffuse alveolar hemorrhage (DAH), a rare complication of coexisting antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE), poses significant diagnostic and therapeutic challenges, especially with recurrent episodes. We present a 27 -year -old male with catastrophic APS and SLE who experienced acute respiratory failure and hemoptysis due to DAH. Despite aggressive therapy with immunosuppressants, plasma exchange, and anticoagulation, he had recurrent DAH episodes requiring repeated admissions. Early recognition, multidisciplinary management, and utilization of effective targeted therapies, such as intravenous immunoglobulin, in refractory cases are crucial for improving outcomes in this challenging complication.

引用

页数：4

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