Physicians' attitudes toward beta-blockers for the treatment of hypertension in Italy, Poland, and Turkey

Despite substantial progress in understanding the complex pathophysiology, hypertension remains a serious public health challenge affecting over 1.2 billion adults aged 30-79 years worldwide. Appropriate knowledge of the different pharmaceutical classes of antihypertensive agents and an understanding of the characteristics of individual molecules are essential to optimize clinical outcomes in patients with hypertension. We conducted a computer-assisted web interviewing (CAWI) quantitative survey in Italy, Poland, and Turkey to investigate physicians' prescriptions, knowledge, and perceptions of antihypertensive drugs with a focus on beta-blockers, to assess antihypertensive usage patterns and the reasons underlying prescription choices. The survey findings show that beta-blockers retain a pivotal role in the management of hypertension and are prescribed more often for patients with cardiovascular comorbidities than for patients with diabetic comorbidities. In all three countries, nebivolol is the only beta-blocker among the ones analyzed which is consistently prescribed to 20% or more of patients and is overall the most prescribed one for the population with comorbid diabetes. In terms of specific beta-blockers' features, this study revealed knowledge gaps that underline the need for educational activities focused on the differences among beta-blockers, which are important in choosing the most suitable agent for individualized antihypertensive therapy.