Synthesis of 1,2′-Spirobi[indene]-1,3-diones by Pd(II)-Catalyzed C-H Activation and Alkynes Annulation Reaction

被引：0

作者：

Xu, Xuefeng ^{[1
]}

Yu, Lintao ^{[1
]}

Chang, Mengfan ^{[1
]}

Wang, Di ^{[1
]}

Shen, Zhi ^{[1
]}

Zhang, Xu ^{[1
]}

机构：

[1] Nanyang Normal Univ, Coll Chem & Pharmaceut Engn, Engn Technol Res Ctr Henan Prov Solar Catalysis, Nanyang 473061, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2024年 / 366卷 / 13期

基金：

中国国家自然科学基金;

关键词：

2-Aryl-1,3-indandiones; Alkynes; Spirobi[indene]-1,3-diones; Palladium Catalyst; CATALYZED OXIDATIVE ANNULATION; BOND-DISSOCIATION ENERGIES; INTERNAL ALKYNES; CHEMOSELECTIVE ACTIVATION; FUNCTIONALIZATION; METAL; DERIVATIVES; 4-HYDROXYCOUMARINS; 2-ALKENYLPHENOLS; DEAROMATIZATION;

D O I：

10.1002/adsc.202400223

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An intermolecular annulation reaction of 2-aryl-1,3-indandions with alkynes was reported using Pd(OAc)2 to access spirobi[indene]-1,3-diones. Under palladium catalysis, the substrates form a homocoupling dimer intermediate through a catalytic dehydrogenative cross-coupling process. The palladium(II) species could come from dimer or 2-aryl-1,3-indandion. Notably, this pathway is not typically observed in enol-directed formal sp3 C-H functionalization/oxidative annulation palladium chemistry. This transformation provides a route to access a class of functionalized spiro carbocyclic indenes. image

引用

页码：2926 / 2932

页数：7

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