Central nervous system lymphoma revealed by lymphocytic meningitis in a patient with systemic lupus erythematosus: An unusual association

被引：1
|
作者：
Roriz, M. [1 ,3 ]
Lopes, A. [1 ]
Jarrin, I. [1 ]
Lechtman, S. [1 ,3 ]
Polivka, M. [2 ]
Bergmann, J. -F. [1 ,3 ]
Sene, D. [1 ,3 ]
Mouly, S. [1 ,3 ]
机构：
[1] Grp Hosp Lariboisiere, Hop Fernand Widal, AP HP, Dept Med Interne, 2 Rue Ambroise Pare, F-75475 Paris 10, France
[2] Hop Lariboisiere, AP HP, Serv Anatomopathol, 2 Rue Ambroise Pare, F-75010 Paris, France
[3] UFR Med Paris Diderot, UMR S1144, 10 Ave Verdun, F-75010 Paris, France
来源：
REVUE DE MEDECINE INTERNE | 2017年 / 38卷 / 04期
关键词：
Lymphoma; Central nervous system; Systemic erythematosus lupus; Meningitis; B-CELL LYMPHOMA; MYCOPHENOLATE-MOFETIL; INFLAMMATORY DISORDERS; AUTOIMMUNE; CNS; MALIGNANCY; DISEASE; RISK;
D O I：
10.1016/j.revmed.2016.05.019
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction. - We report an unusual observation of central nervous system (CNS) lymphoma in a 60 year-old woman with systemic lupus erythematosus and fatal outcome. Observation. - The patient had systemic erythematosus lupus for 7 years, treated with mycophenolate mofetil and developed lymphocytic meningitis in 2015 associated to the presence of EBV in the cerebrospinal fluid and a necrotic vermis' lesion. Diagnosis of large B-cell lymphoma was histologically confirmed from stereotaxic biopsy, shortly before she died from neurological complications. Conclusion. - Even though the current association is unusual, lymphocytic meningitis with hypogly-corrachia in patients with systemic lupus erythematosus may reveal CNS lymphoma and diagnosis confirmation requires stereotaxic biopsy in order not to delay specific therapeutic management. (C) 2016 Societe Nationale Francaise de Medecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：269 / 273
页数：5
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