Myocardical Infarction with Non-Obstructive Coronary Arteries (MINOCA): pathogenesis, diagnosis and treatment

被引：6

作者：

Sucato, Vincenzo ^{[1
,2
]}

Comparato, Francesco ^{[1
]}

Ortello, Antonella ^{[1
]}

Galassi, Alfredo Ruggero ^{[1
]}

机构：

[1] Univ Palermo, Paolo Giaccone Hosp, Dept Excellence Sci Hlth Promot & Maternal Child C, Div Cardiol, Palermo, Italy

[2] Univ Palermo, Paolo Giaccone Hosp, Dept PROMISE, Div Cardiol, Via Vespro 147, I-90127 Palermo, Italy

来源：

CURRENT PROBLEMS IN CARDIOLOGY | 2024年 / 49卷 / 07期

关键词：

Cardiac magnetic resonance; Coronary microvascular dysfunction; Intravascular imaging; MINOCA; Myocardial infarction; CARDIAC MAGNETIC-RESONANCE; CLINICAL-FEATURES; CHEST-PAIN; PERICARDIAL DISEASES; GENDER-DIFFERENCES; VULNERABLE PLAQUE; EUROPEAN-SOCIETY; POSITION PAPER; DISSECTION; ASSOCIATION;

D O I：

10.1016/j.cpcardiol.2024.102583

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The term MINOCA (Myocardial Infarction with Non -Obstructive Coronary Arteries) refers to myocardial infarction cases where coronary arteries exhibit less than 50 % stenosis. MINOCA encompasses a diverse range of pathologies with varying etiologies. Diagnosis involves meeting acute myocardial infarction criteria and excluding other causes (myocarditis, takotsubo syndrome). Clinical features often resemble those of traditional myocardial infarction, but MINOCA patients tend to be younger and more frequently female. Etiological investigations include coronary angiography, intracoronary imaging, and vasomotor function tests. Causes include plaque rupture, coronary dissection, vasospasm, microvascular dysfunction, thromboembolism. Prognosis varies, with some subsets at higher risk. Management involves a tailored approach addressing underlying causes, with emphasis on cardioprotective therapy, risk factor modification, and lifestyle interventions. Further research is needed to refine diagnostic strategies and optimize therapeutic approaches in MINOCA patients.

引用

页数：9

共 72 条

[61] Myocardial infarction with non-obstructive coronary arteries (MINOCA): Intracoronary imaging-based diagnosis and management
Sucato, Vincenzo
Testa, Gabriella
Puglisi, Sebastiano
Evola, Salvatore
Galassi, Alfredo Ruggero
Novo, Giuseppina
[J]. JOURNAL OF CARDIOLOGY, 2021, 77 (05) : 444 - 451
[62] Ischemia in the absence of obstructive coronary artery disease (INOCA): microvascular angina and vasospastic angina
Sucato, Vincenzo
Novo, Salvatore
Manno, Girolamo
Coppola, Giuseppe
Caronna, Nicola
Evola, Salvatore
Corrado, Egle
Novo, Giuseppina
Galassi, Alfredo Ruggero
[J]. GIORNALE ITALIANO DI CARDIOLOGIA, 2020, 21 (12) : 954 - 960
[63] Ischemia in patients with no obstructive coronary artery disease: classification, diagnosis and treatment of coronary microvascular dysfunction
Sucato, Vincenzo
Novo, Giuseppina
Saladino, Antonino
Rubino, Marianna
Caronna, Nicola
Luparelli, Mirko
D'Agostino, Alessandro
Novo, Salvatore
Evola, Salvatore
Galassi, Alfredo Ruggero
[J]. CORONARY ARTERY DISEASE, 2020, 31 (05) : 472 - 476
[64] Coronary microvascular dysfunction
Sucato, Vincenzo
Novo, Giuseppina
Saladino, Antonino
Evola, Salvatore
Galassi, Alfredo R.
[J]. MINERVA CARDIOANGIOLOGICA, 2020, 68 (02): : 153 - 163
[65] Prognosis in patients with microvascular angina: a clinical follow-up
Sucato, Vincenzo
Novo, Salvatore
Rubino, Marianna
D'Agostino, Alessandro
Evola, Salvatore
Novo, Giuseppina
[J]. JOURNAL OF CARDIOVASCULAR MEDICINE, 2019, 20 (11) : 794 - 795
[66] Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association
Tamis-Holland, Jacqueline E.
Jneid, Hani
Reynolds, Harmony R.
Agewall, Stefan
Brilakis, Emmanouil S.
Brown, Todd M.
Lerman, Amir
Cushman, Mary
Kumbhani, Dharam J.
Arslanian-Engoren, Cynthia
Bolger, Ann F.
Beltrame, John F.
[J]. CIRCULATION, 2019, 139 (18) : E891 - E908
[67] Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy
Templin, C.
Ghadri, J. R.
Diekmann, J.
Napp, L. C.
Bataiosu, D. R.
Jaguszewski, M.
Cammann, V. L.
Sarcon, A.
Geyer, V.
Neumann, C. A.
Seifert, B.
Hellermann, J.
Schwyzer, M.
Eisenhardt, K.
Jenewein, J.
Franke, J.
Katus, H. A.
Burgdorf, C.
Schunkert, H.
Moeller, C.
Thiele, H.
Bauersachs, J.
Tschoepe, C.
Schultheiss, H-P.
Laney, C. A.
Rajan, L.
Michels, G.
Pfister, R.
Ukena, C.
Boehm, M.
Erbel, R.
Cuneo, A.
Kuck, K-H.
Jacobshagen, C.
Hasenfuss, G.
Karakas, M.
Koenig, W.
Rottbauer, W.
Said, S. M.
Braun-Dullaeus, R. C.
Cuculi, F.
Banning, A.
Fischer, T. A.
Vasankari, T.
Airaksinen, K. E. J.
Fijalkowski, M.
Rynkiewicz, A.
Pawlak, M.
Opolski, G.
Dworakowski, R.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (10) : 929 - 938
[68] Thygesen K, 2012, EUR HEART J, V33, P2551, DOI [10.1016/j.gheart.2018.08.004, 10.1093/eurheartj/ehs184, 10.1161/CIR.0b013e31826e1058, 10.1016/j.gheart.2012.08.001, 10.1016/j.jacc.2012.08.001, 10.1016/j.clinbiochem.2012.10.036, 10.5603/KP.2018.0203]
[69] Myocarditis or "true" infarction by cardiac magnetic resonance in patients with a clinical diagnosis of myocardial infarction without obstructive coronary disease: A meta-analysis of individual patient data
Tornvall, P.
Gerbaud, E.
Behaghel, A.
Chopard, R.
Collste, O.
Laraudogoitia, E.
Leurent, G.
Meneveau, N.
Montaudon, M.
Perez-David, E.
Soerensson, P.
Agewall, S.
[J]. ATHEROSCLEROSIS, 2015, 241 (01) : 87 - 91
[70] Platelet Inhibition, Endothelial Function, and Clinical Outcome in Patients Presenting With ST-Segment-Elevation Myocardial Infarction Randomized to Ticagrelor Versus Prasugrel Maintenance Therapy: Long-Term Follow-Up of the REDUCE-MVI Trial
van der Hoeven, Nina W.
Janssens, Gladys N.
Everaars, Henk
Nap, Alexander
Lemkes, Jorrit S.
de Waard, Guus A.
van de Ven, Peter M.
van Rossum, Albert C.
Escaned, Javier
Mejia-Renteria, Hernan
ten Cate, Tim J. F.
Piek, Jan J.
von Birgelen, Clemens
Valgimigli, Marco
Diletti, Roberto
Riksen, Niels P.
Van Mieghem, Nicolas M.
Nijveldt, Robin
van Leeuwen, Maarten A. H.
van Royen, Niels
[J]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2020, 9 (05):

← 1 2 3 4 5 6 7 8 →