Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives

被引：4

作者：

Nandwana, Nitesh K. ^{[1
]}

Patel, Om P. S. ^{[2
]}

Mehra, Manish K. ^{[1
]}

Kumar, Anil ^{[3
]}

Salvino, Joseph M. ^{[1
]}

机构：

[1] Wistar Inst Anat & Biol, Med Chem & Mol & Cellular Oncogenesis MCO Program, Philadelphia, PA 19104 USA

[2] Govt Polytech Naraini, Dept Tech Educ, Banda 210001, India

[3] Birla Inst Technol & Sci, Dept Chem, Pilani 333031, India

来源：

MOLECULES | 2024年 / 29卷 / 10期

关键词：

quinazoline heterocycles; transition metal-catalyzed synthesis; C-H activation; cascade reactions; intramolecular dehydrative/dehydrogenative cyclizations; ONE-POT SYNTHESIS; AEROBIC OXIDATIVE SYNTHESIS; C-H ACTIVATION; CASCADE SYNTHESIS; 3-COMPONENT SYNTHESIS; EFFICIENT SYNTHESIS; TANDEM REACTIONS; DOMINO REACTION; DEHYDROGENATIVE SYNTHESIS; SUBSTITUTED QUINAZOLINES;

D O I：

10.3390/molecules29102353

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.

引用

页数：54

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