Colchicine and Risk of Venous Thromboembolism: A Systematic Review and Meta-analysis of Randomized Controlled Trials

被引：0

作者：

Wang, Michael K. ^{[1
,2
]}

Razeghi, Ghazal ^{[3
]}

Eikelboom, John W. ^{[1
,2
]}

Devereaux, P. J. ^{[1
,2
,4
]}

Budgeon, Charley A. ^{[3
,5
]}

Jacka, Michael J. ^{[6
]}

Wright, David J. ^{[7
]}

Latini, Roberto ^{[8
]}

Conen, David ^{[1
,2
,4
]}

机构：

[1] McMaster Univ, Populat Hlth Res Inst, Hamilton, ON, Canada

[2] McMaster Univ, Dept Med, Hamilton, ON, Canada

[3] McMaster Univ, Michael G DeGroote Sch Med, Hamilton, ON, Canada

[4] McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada

[5] Univ Western Australia, Sch Populat & Global Hlth, Perth, Australia

[6] Univ Alberta, Edmonton, AB, Canada

[7] Liverpool Heart & Chest Hosp, Liverpool, England

[8] Mario Negri Inst Pharmacol Res IRCCS, Dept Cardiovasc Res, Milan, Italy

来源：

CANADIAN JOURNAL OF CARDIOLOGY | 2024年 / 40卷 / 07期

关键词：

D O I：

10.1016/j.cjca.2023.12.036

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Colchicine is an inexpensive anti-inflammatory drug used for treating gout and pericarditis. Two large randomized controlled trials (RCTs) showed that colchicine prevents adverse cardiovascular outcomes such as myocardial infarction, stroke, and cardiovascular death in patients with coronary artery disease.1,2 Some trials have suggested that there might be a greater risk of venous thromboembolism (VTE) systematic review and meta-analysis of RCTs to determine the effect of colchicine on the risk of VTE.

引用

页码：1344 / 1346

页数：3

共 5 条

[1] Effect of colchicine on perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery (COP-AF): an international randomised trial [J].

Conen, David ;

Wang, Michael Ke ;

Popova, Ekaterine ;

Chan, Matthew T., V ;

Landoni, Giovanni ;

Cata, Juan P. ;

Reimer, Cara ;

McLean, Sean R. ;

Srinathan, Sadeesh K. ;

Reyes, Juan Carlos Trujillo ;

Grande, Ascension Martin ;

Tallada, Anna Gonzalez ;

Sessler, Daniel, I ;

Fleischmann, Edith ;

Kabon, Barbara ;

Voltolini, Luca ;

Cruz, Patricia ;

Maziak, Donna E. ;

Gutierrez-Soriano, Laura ;

Mcintyre, William F. ;

Tandon, Vikas ;

Martinez-Tellez, Elisabeth ;

Guerra-Londono, Juan Jose ;

DuMerton, Deborah ;

Wong, Randolph H. L. ;

McGuire, Anna L. ;

Kidane, Biniam ;

Roux, Diego Parise ;

Shargall, Yaron ;

Wells, Jennifer R. ;

Ofori, Sandra N. ;

Vincent, Jessica ;

Xu, Lizhen ;

Li, Zhuoru ;

Eikelboom, John W. ;

Jolly, Sanjit S. ;

Healey, Jeff S. ;

Devereaux, P. J. .

LANCET, 2023, 402 (10413) :1627-1635

[2] Colchicine in Cardiovascular Disease: In-Depth Review [J].

Deftereos, Spyridon G. ;

Beerkens, Frans J. ;

Shah, Binita ;

Giannopoulos, George ;

Vrachatis, Dimitrios A. ;

Giotaki, Sotiria G. ;

Siasos, Gerasimos ;

Nicolas, Johny ;

Arnott, Clare ;

Patel, Sanjay ;

Parsons, Mark ;

Tardif, Jean-Claude ;

Kovacic, Jason C. ;

Dangas, George D. .

CIRCULATION, 2022, 145 (01) :61-78

[3] Colchicine in Patients with Chronic Coronary Disease [J].

Nidorf, Stefan M. ;

Fiolet, Aernoud T. L. ;

Mosterd, Arend ;

Eikelboom, John W. ;

Schut, Astrid ;

Opstal, Tjerk S. J. ;

The, Salem H. K. ;

Xu, Xiao-Fang ;

Ireland, Mark A. ;

Lenderink, Timo ;

Latchem, Donald ;

Hoogslag, Pieter ;

Jerzewski, Anastazia ;

Nierop, Peter ;

Whelan, Alan ;

Hendriks, Randall ;

Swart, Henk ;

Schaap, Jeroen ;

Kuijper, Aaf F. M. ;

van Hessen, Maarten W. J. ;

Saklani, Pradyot ;

Tan, Isabel ;

Thompson, Angus G. ;

Morton, Allison ;

Judkins, Chris ;

Bax, Willem A. ;

Dirksen, Maurits ;

Alings, Marco ;

Hankey, Graeme J. ;

Budgeon, Charley A. ;

Tijssen, Jan G. P. ;

Cornel, Jan H. ;

Thompson, Peter L. .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (19) :1838-1847

[4] Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial [J].

Tardif, Jean-Claude ;

Bouabdallaoui, Nadia ;

L'Allier, Philippe L. ;

Gaudet, Daniel ;

Shah, Binita ;

Pillinger, Michael H. ;

Lopez-Sendon, Jose ;

da Luz, Protasio ;

Verret, Lucie ;

Audet, Sylvia ;

Dupuis, Jocelyn ;

Denault, Andre ;

Pelletier, Martin ;

Tessier, Philippe A. ;

Samson, Sarah ;

Fortin, Denis ;

Tardif, Jean-Daniel ;

Busseuil, David ;

Goulet, Elisabeth ;

Lacoste, Chantal ;

Dubois, Anick ;

Joshi, Avni Y. ;

Waters, David D. ;

Hsue, Priscilla ;

Lepor, Norman E. ;

Lesage, Frederic ;

Sainturet, Nicolas ;

Roy-Clavel, Eve ;

Bassevitch, Zohar ;

Orfanos, Andreas ;

Stamatescu, Gabriela ;

Gregoire, Jean C. ;

Busque, Lambert ;

Lavallee, Christian ;

Hetu, Pierre-Olivier ;

Paquette, Jean-Sebastien ;

Deftereos, Spyridon G. ;

Levesque, Sylvie ;

Cossette, Marieve ;

Nozza, Anna ;

Chabot-Blanchet, Malorie ;

Dube, Marie-Pierre ;

Guertin, Marie-Claude ;

Boivin, Guy .

LANCET RESPIRATORY MEDICINE, 2021, 9 (08) :924-932

[5] Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction [J].

Tardif, Jean-Claude ;

Kouz, Simon ;

Waters, David D. ;

Bertrand, Olivier F. ;

Diaz, Rafael ;

Maggioni, Aldo P. ;

Pinto, Fausto J. ;

Ibrahim, Reda ;

Gamra, Habib ;

Kiwan, Ghassan S. ;

Berry, Colin ;

Lopez-Sendon, Jose ;

Ostadal, Petr ;

Koenig, Wolfgang ;

Angoulvant, Denis ;

Gregoire, Jean C. ;

Lavoie, Marc-Andre ;

Dube, Marie-Pierre ;

Rhainds, David ;

Provencher, Mylene ;

Blondeau, Lucie ;

Orfanos, Andreas ;

L'Allier, Philippe L. ;

Guertin, Marie-Claude ;

Roubille, Francois .

NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (26) :2497-2505

← 1 →