Effects of sex on fat deposition through gut microbiota and shortchain fatty acids in weaned pigs

被引：4

作者：

Yao, Linfang ^{[1
]}

Wang, Bo ^{[1
]}

Wang, Yu ^{[1
]}

Bai, Jie ^{[1
]}

Gao, Yiming ^{[1
]}

Ru, Xintong ^{[1
]}

Bi, Chongpeng ^{[1
]}

Li, Jianping ^{[1
]}

Shan, Anshan ^{[1
]}

机构：

[1] Northeast Agr Univ, Coll Anim Sci & Technol, Harbin 150030, Peoples R China

来源：

ANIMAL NUTRITION | 2024年 / 17卷

关键词：

Sex; Body composition; Nutrient deposition; Gut microbiota; Short-chain fatty acid; Weaned piglet; PROTEIN RESTRICTION; GROWTH-PERFORMANCE; ENERGY; BUTYRATE; NITROGEN; DIETS;

D O I：

10.1016/j.aninu.2024.03.004

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Nitrogen pollution resulting from excessive feed consumption poses a signi ficant challenge for modern swine production. Precision nutrition technology seems to be an effective way to solve this problem; therefore, understanding the law of pig body composition deposition is a prerequisite. This study investigated the sex effects on growth performance, body composition, nutrient deposition, gut microbiota, and short -chain fatty acids (SCFA) in weaned piglets. Eighty weaned pigs were randomly allocated to 2 treatments according to the sex of pigs. An individual pig was considered as a treatment replicate. Six body weights (BW 5, 7,11,15, 20, and 25 kg) were chosen as experimental points; for each point 10 piglets close to the average BW (5 males and 5 females) were slaughtered, and there was one growth phase between each 2 BW points. Results indicated that the males had higher average daily gain (ADG) and average daily feed intake (ADFI) compared to the females ( P < 0.05) at growth phases 15 to 20 kg BW and 20 to 25 kg BW. Meanwhile, males at 20 kg BW had higher body fat content than females ( P < 0.10). Males showed a higher body fat ( P < 0.05) deposition rate at phase 15 to 20 kg BW ( P < 0.05) than females. For pigs at 20 kg BW, the relative abundance of Ruminococcaceae UCG-005 , Clostridium , Christensenellaceae_R-7_group , and Peptostreptococcaceae was signi ficantly increased in males ( P < 0.05) but that of Bi fi dobacterium was decreased ( P < 0.05). At 25 kg BW, the relative abundance of Ruminococcaceae_NK4A214_group , Fibrobacter , Ruminococcaceae UCG-009 , Ralstonia , Klebsiel , and Christensenellaceae_R-7_group in males was higher when compared with females ( P < 0.05). In terms of SCFA, females exhibited higher concentrations of propionate compared to males ( P < 0.05). The results of the current study indicated that sex in fluenced fat deposition through changes in the composition of gut microbiota and the content of SCFA, which has signi ficant implications for the realization of precision nutrition in modern swine production.

引用

页码：100 / 109

页数：10

共 67 条

[41] Rearing pattern alters porcine myofiber type, fat deposition, associated microbial communities and functional capacity [J].

Qi, Keke ;

Men, Xiaoming ;

Wu, Jie ;

Xu, Ziwei .

BMC MICROBIOLOGY, 2019, 19 (01)

[42] Instant Dark Tea Alleviates Hyperlipidaemia in High-Fat Diet-Fed Rat: From Molecular Evidence to Redox Balance and Beyond [J].

Qin, Si ;

He, Zhilan ;

Wu, Yuanjie ;

Zeng, Chaoxi ;

Zheng, Zhibing ;

Zhang, Haowei ;

Lv, Chenghao ;

Yuan, Yong ;

Wu, Haoren ;

Ye, Jianhui ;

Liu, Zhonghua ;

Shi, Meng .

FRONTIERS IN NUTRITION, 2022, 9

[43] Connecting the immune system, systemic chronic inflammation and the gut microbiome: The role of sex [J].

Rizzetto, Lisa ;

Fava, Francesca ;

Tuohy, Kieran M. ;

Selmi, Carlo .

JOURNAL OF AUTOIMMUNITY, 2018, 92 :12-34

[44] Body tissue and chemical component deposition in Nellore bulls, steers and heifers [J].

Rodrigues Paulino, Pedro Veiga ;

Valadares Filho, Sebastiao de Campos ;

Detmann, Edenio ;

Diniz Valadares, Rilene Ferreira ;

Fonseca, Mozart Alves ;

Marcondes, Marcos Inacio .

REVISTA BRASILEIRA DE ZOOTECNIA-BRAZILIAN JOURNAL OF ANIMAL SCIENCE, 2009, 38 (12) :2516-2524

[45] Early Parenteral Administration of Ceftiofur has Gender-Specific Short- and Long-Term Effects on the Fecal Microbiota and Growth in Pigs from the Suckling to Growing Phase [J].

Ruczizka, Ursula ;

Metzler-Zebeli, Barbara ;

Unterweger, Christine ;

Mann, Evelyne ;

Schwarz, Lukas ;

Knecht, Christian ;

Hennig-Pauka, Isabel .

ANIMALS, 2020, 10 (01)

[46] Testosterone metabolites differentially regulate obesogenesis and fat distribution [J].

Sebo, Zachary L. ;

Rodeheffer, Matthew S. .

MOLECULAR METABOLISM, 2021, 44

[47] Protein restriction and succedent realimentation affecting ileal morphology, ileal microbial composition and metabolites in weaned piglets [J].

Shi, Q. ;

Zhu, Y. ;

Wang, J. ;

Yang, H. ;

Zhu, W. .

ANIMAL, 2019, 13 (11) :2463-2472

[48]

Soares E, 2021, Biomed Pharmacother, P144

[49] Analysis of sex differences in dietary copper-fructose interaction-induced alterations of gut microbial activity in relation to hepatic steatosis [J].

Song, Ming ;

Yuan, Fang ;

Li, Xiaohong ;

Ma, Xipeng ;

Yin, Xinmin ;

Rouchka, Eric C. ;

Zhang, Xiang ;

Deng, Zhongbin ;

Prough, Russell A. ;

McClain, Craig J. .

BIOLOGY OF SEX DIFFERENCES, 2021, 12 (01)

[50] The effects of birth weight and estimated breeding value for protein deposition on nitrogen efficiency in growing pigs [J].

Van der Peet-Schwering, Carola M. C. ;

Verschuren, Lisanne M. G. ;

Bergsma, Rob ;

Hedemann, Mette S. ;

Binnendijk, Gisabeth P. ;

Jansman, Alfons J. M. .

JOURNAL OF ANIMAL SCIENCE, 2021, 99 (06)

← 1 2 3 4 5 6 7 →