Variable Expression Common Immune Deficiency: A Report of Five Cases

被引:0
|
作者
Bouhamdi, Abir [1 ]
Serraj, Mounia [1 ]
Biaz, Mohamed [1 ]
Benjelloun, Mohamed Chakib [1 ]
Amara, Bouchra [1 ]
机构
[1] Univ Sidi Mohammed Ben Abdellah, Hassan Univ Hosp 2, Pulmonol Dept, Fes, Morocco
关键词
systemic granulomatosis; intravenous immunoglobulins (ivig); serum protein electrophoresis (spep); bronchial dilatation; variable common immune deficiency; IMMUNODEFICIENCY DISORDERS; IMMUNOLOGICAL FEATURES; DIAGNOSTIC-CRITERIA; IMMUNOGLOBULIN;
D O I
10.7759/cureus.61397
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We present five cases of common variable immunodeficiency (CVID), comprising three women and two men with a mean age of 23.8 +/- 9.2 years. All our patients suffered from recurrent bronchopneumonitis, with complications of purulent pleurisy in two cases, requiring decortication in one case, and resulting in bronchiectasis in three cases. Digestive tract infections were observed in four patients, while two patients presented with ENT infections. One case was complicated by bacterial meningitis. All patients presented with global hypogammaglobulinemia, with CVID and granulomatous manifestation in one case. Treatment consisted of monthly immunoglobulin infusions.
引用
收藏
页数:7
相关论文
共 48 条
  • [21] Defining B-cell defects and correlation with complications in patients with common variable immune deficiency
    Chapel, Helen
    Patel, Smita
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 144 (03) : 654 - 655
  • [22] Chronic lung disease in common variable immune deficiency (CVID): A pathophysiological role for microbial and non-B cell immune factors
    Mooney, Denver
    Edgar, David
    Einarsson, Gisli
    Downey, Damian
    Elborn, Stuart
    Tunney, Michael
    CRITICAL REVIEWS IN MICROBIOLOGY, 2017, 43 (04) : 508 - 519
  • [23] Differentiation of Common Variable Immunodeficiency From IgG Deficiency
    Filion, Charles A.
    Taylor-Black, Sarah
    Maglione, Paul J.
    Radigan, Lin
    Cunningham-Rundles, Charlotte
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2019, 7 (04) : 1277 - 1284
  • [24] New diagnostic criteria for common variable immune deficiency (CVID), which may assist with decisions to treat with intravenous or subcutaneous immunoglobulin
    Ameratunga, R.
    Woon, S. -T.
    Gillis, D.
    Koopmans, W.
    Steele, R.
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2013, 174 (02) : 203 - 211
  • [25] Chemokine, cytokine and type I interferon production induced by Toll-like receptor activation in common variable immune deficiency
    de Lollo, Camila
    Vasconcelos, Dewton de Moraes
    da Silva Oliveira, Luanda Mara
    Domingues, Rosana
    de Carvalho, Gabriel Costa
    da Silva Duarte, Alberto Jose
    Sato, Maria Notomi
    CLINICAL IMMUNOLOGY, 2016, 169 : 121 - 127
  • [26] Suspected Pediatric-Onset Common Variable Immune Deficiency (CVID) in a Seven-Year-Old Female With Pulmonary Manifestations
    Noor, Noshaba
    Ghori, Mariam
    Molani, Rameen A.
    Ibrahim, Mohsina N.
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (09)
  • [27] Microbial Dysbiosis in Common Variable Immune Deficiencies: Evidence, Causes, and Consequences
    Berbers, Roos-Marijn
    Nierkens, Stefan
    van Laar, Jacob M.
    Bogaert, Debby
    Leavis, Helen L.
    TRENDS IN IMMUNOLOGY, 2017, 38 (03) : 206 - 216
  • [28] AICDA single nucleotide polymorphism in common variable immunodeficiency and selective IgA deficiency
    Farhadi, E.
    Nemati, S.
    Amirzargar, A. A.
    Hirbod-Mobarakeh, A.
    Nabavi, M.
    Soltani, S.
    Mahdaviani, S. A.
    Shahinpour, S.
    Arshi, S.
    Nikbin, B.
    Aghamohammadi, A.
    Rezaei, N.
    ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2014, 42 (05) : 422 - 426
  • [29] Macroaspartate aminotransferase. Report of five cases and a review of the literature
    Goenner, S
    Corriat-Boutron, A
    Pelletier, G
    Legrand, A
    Buffet, C
    GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE, 1998, 22 (05): : 549 - 553
  • [30] Neonatal presentation of Prader-Willi syndrome: A report of five cases
    Richard-De Ceaurriz, B.
    Leymarie, C.
    Godefroy, A.
    Collignon, P.
    Sigaudy, S.
    Truc, P.
    ARCHIVES DE PEDIATRIE, 2017, 24 (11): : 1115 - 1120