Psychiatric implications of anti-seizure medications in epileptic population

被引:1
|
作者
Khalid, Bushra [1 ]
Waqar, Zaid [1 ]
Khan, Soban [1 ]
Ali, Ijaz [1 ]
Afzal, Naheed [1 ]
Irfan, Anum [1 ]
Malik, Waleed [1 ]
Adil, Malik Muhammad [1 ]
Saddiqa, Amina [1 ]
Khalil, Maryam [1 ]
Munawar, Zeeshan [1 ]
机构
[1] Pakistan Inst Med Sci, Islamabad, Pakistan
关键词
Epilepsy; Antiseizure medications; Psychiatric comorbidities; Valproate; MRI findings; DEPRESSION; CLASSIFICATION; COMORBIDITIES; DEFINITION; ILAE;
D O I
10.1186/s12883-024-03670-8
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and objective Epilepsy is a prevalent neurological disorder that affects a significant number of individuals globally. This condition is associated with a high occurrence of psychiatric comorbidities, which can significantly affect the quality of life of individuals affected. The aim of this study was to investigate the association between antiseizure therapies and the likelihood of psychiatric comorbidities in individuals with epilepsy.Methodology Data for this study was gathered from the Neurology referral center in Islamabad, Pakistan. A standardized questionnaire was utilized to gather data from 120 individuals diagnosed with epilepsy. The survey consisted of inquiries regarding the management of seizures, the utilization of anti-seizure medications, and the presence of psychiatric comorbidities. The data was analyzed using the Statistical Package for the Social Sciences (SPSS).Results The findings indicated that individuals who were using multiple antiseizure medications had a notably higher likelihood of having psychiatric comorbidities in comparison to those who were on mono therapy (p = 0.010). suggests that patients with unsuccessful seizure control are more probable to have psychiatric comorbidities as compared to those with good seizure control (p = 0.029).Conclusion To conclude poor seizure control and poly therapy are associated with increased risk of psychiatric comorbidities.
引用
收藏
页数:5
相关论文
共 50 条
  • [1] The Effect of Anti-seizure Medications on the Propagation of Epileptic Activity: A Review
    Khateb, Mohamed
    Bosak, Noam
    Herskovitz, Moshe
    FRONTIERS IN NEUROLOGY, 2021, 12
  • [2] Is It the Remedy or the Disease? Psychiatric Symptoms Related to Anti-Seizure Medications
    Bermeo-Ovalle, Adriana
    EPILEPSY CURRENTS, 2018, 18 (06) : 369 - 371
  • [3] Discontinuation of anti-seizure medications: A population-wide analysis
    Idegard, A.
    Zelano, J.
    EPILEPSIA, 2024, 65 : 174 - 174
  • [4] EPILEPTIC SEIZURES, ANTI-SEIZURE MEDICATIONS, AND NEUROCOGNITION IN SURVIVORS OF PEDIATRIC BRAIN TUMORS
    Licht, Edvard de Fine
    Ideland, Tova
    Sigurdsson, Gunnar
    Anastasopoulou, Stavroula
    Olsson, Ingrid Tonning
    NEURO-ONCOLOGY, 2024, 26
  • [5] DONT SWITCH ANTI-SEIZURE MEDICATIONS
    ALLEN, MA
    AMERICAN JOURNAL OF NURSING, 1988, 88 (02) : 166 - &
  • [6] Anti-seizure Medications: Challenges and Opportunities
    Tandon, Neha
    Radosavljevic, Milica
    Vucevic, Danijela
    Radenkovic, Miroslav
    Jancic, Jasna
    Samardzic, Janko
    CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2024, 23 (09) : 1120 - 1133
  • [7] Anti-seizure medications and intelligence quotient
    Boshuisen K
    van Schooneveld MM
    Uiterwaal CS
    中华物理医学与康复杂志, 2015, (09) : 720 - 720
  • [8] Pregnancy, anti-seizure medications, and seizures
    Karceski, Steven
    NEUROLOGY, 2018, 91 (13) : E1271 - E1272
  • [9] Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies
    Adam Strzelczyk
    Susanne Schubert-Bast
    CNS Drugs, 2022, 36 : 1079 - 1111
  • [10] Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies
    Strzelczyk, Adam
    Schubert-Bast, Susanne
    CNS DRUGS, 2022, 36 (10) : 1079 - 1111