Preoperative iron infusion does not reduce the requirement for blood transfusion in colorectal cancer surgery

被引:0
作者
Anthony, Phelopatir [1 ,3 ]
Wu, Mike [1 ]
Shanmugalingam, Aswin [1 ]
Ng, Cheuk H. [2 ]
Wright, Danette [1 ]
机构
[1] Blacktown Hosp, Dept Surg, Blacktown, Australia
[2] Westmead Hosp, Dept Surg, Westmead, Australia
[3] Blacktown Hosp, Dept Gen Surg, 18 Blacktown Rd, Blacktown, NSW 2148, Australia
来源
MINERVA SURGERY | 2024年 / 79卷 / 01期
关键词
Ferric compounds; Teferrol; Colorectal surgery; Colonic neoplasms; Blood transfusion; SERUM FERRITIN; DEFICIENCY; ANEMIA;
D O I
10.23736/S27245691.23.09975-6
中图分类号
R61 [外科手术学];
学科分类号
摘要
BACKGROUND: Allogeneic blood transfusions (BT) for patients undergoing colorectal cancer surgery have demonstrated to increase postoperative morbidity and mortality. It has been suggested that the utilization of preoperative iron infusions may reduce the requirement for allogeneic BT in these patients. The aim of this project is to ascertain whether the preoperative use of intravenous iron is significantly associated with a reduction in perioperative blood transfusion requirement. METHODS: A retrospective study of 130 patients was conducted in Blacktown Hospital, Australia. Data pertaining to patient demographics, as well as quantity of preoperative iron infusion and perioperative blood transfusion was collected. RESULTS: Twenty-six (20%) patients required perioperative BT. Twenty-seven underwent preoperative iron infusion, with 20 of them not requiring BT and seven requiring BT. There was no evidence to suggest preoperative iron infusion reduces blood transfusion requirement (RR 1.55, 95% CI 0.57-4.18, P=0.39). For elective procedures, no significance was also demonstrated (RR 1.20, 95% CI 0.29-4.92, P=0.80). CONCLUSIONS: There is no evidence suggesting that preoperative iron infusion reduces the requirement for perioperative blood transfusion in colorectal cancer surgery.
引用
收藏
页码:28 / 32
页数:5
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