Paeoniae Radix Rubra:A Review of Ethnopharmacology, Phytochemistry, Pharmacological Activities, Therapeutic Mechanism for Blood Stasis Syndrome, and Quality Control

被引：11

作者：

Fan, Zuowang ^{[1
,2
]}

Liu, Jing ^{[1
]}

Wang, Xu ^{[1
]}

Yang, Saisai ^{[1
]}

Wang, Qi ^{[1
]}

Yan, Li ^{[1
]}

Zhang, Yao ^{[1
]}

Wu, Xiuhong ^{[1
]}

机构：

[1] Heilongjiang Univ Chinese Med, Sch Pharm, Harbin 150040, Peoples R China

[2] Sanming Med & Polytech Vocat Coll, Sanming 365000, Peoples R China

来源：

CHEMISTRY & BIODIVERSITY | 2024年 / 21卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Paeoniae radix rubra; Ethnopharmacology; Phytochemistry; Pharmacology; Quality control; MONOTERPENE GLYCOSIDES; PEONY ROOT; PAEONIFLORIN; LACTIFLORA; DERIVATIVES; ALBIFLORIN; RATS; CONSTITUENTS; GLUCOSIDES; EXTRACT;

D O I：

10.1002/cbdv.202401119

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Paeoniae Radix Rubra (PRR) known as Chishao, in China, is the dried root of Paeonia lactiflora Pall. or Paeonia veitchii Lynch, with a history of over 2000 years in traditional Chinese medicine, is employed to clear heat, cool the blood, dispel blood stasis, and alleviate pain. Phytochemical investigations identified 264 compounds that contained monoterpenes and their glycosides, sesquiterpenes, triterpenes, steroids, flavonoids, lignans, tannins, volatile oils, and other compounds. It has been reported to have different pharmacological activities, including cardiovascular-protective, antidepressive, neuroprotective, antitumor, hepatoprotective, and anti-inflammatory effects. This study offers a comprehensive review covering ethnopharmacology, phytochemistry, pharmacological activities, therapeutic mechanism for blood stasis syndrome, and quality control of PRR. The comprehensive analysis aims to achieve a thorough understanding of its effects and serves as a foundation for future research and development. image

引用

页数：24

共 154 条

[1]

Abdel-Hafez AA, 1998, BIOL PHARM BULL, V21, P1174, DOI 10.1248/bpb.21.1174

[2]

[Anonymous], 1985, CHINESE PHARMACOPOEI, P139

[3]

[Anonymous], 2020, CHINESE PHARMACOPOEI, P165

[4] Protective effect of a molecular chaperone inducer, paeoniflorin, on the HCl- and ethanol-triggered gastric mucosal injury [J].

Asai, Midori ;

Kawashima, Daisuke ;

Katagiri, Kiyoe ;

Takeuchi, Rika ;

Tohnai, Genki ;

Ohtsuka, Kenzo .

LIFE SCIENCES, 2011, 88 (7-8) :350-357

[5] New monoterpene glycosides from Paeonia lactiflora [J].

Braca, Alessandra ;

Van Kiem, Phan ;

Yen, Pham Hai ;

Nhiem, Nguyen Xuan ;

Quang, Tran Hong ;

Cuong, Nguyen Xuan ;

Van Minh, Chau .

FITOTERAPIA, 2008, 79 (02) :117-120

[6] Paeoniflorin suppresses kidney inflammation by regulating macrophage polarization via KLF4-mediated mitophagy [J].

Cao, Yiwen ;

Xiong, Jingli ;

Guan, Xueping ;

Yin, Simin ;

Chen, Junqi ;

Yuan, Shengliang ;

Liu, Hong ;

Lin, Shuyin ;

Zhou, Yuan ;

Qiu, Jianguang ;

Wang, Dejuan ;

Liu, Bihao ;

Zhou, Jiuyao .

PHYTOMEDICINE, 2023, 116

[7]

Chen J, 2018, FOOD FUNCT, V9, P2386, DOI [10.1039/c7fo01406f, 10.1039/C7FO01406F]

[8]

Chen T, 2011, CAN J PHYSIOL PHARM, V89, P445, DOI [10.1139/Y11-034, 10.1139/y11-034]

[9]

Chen Y., 2017, CHIN ARCH TRADIT CHI, V35, P205

[10] Paeonia lactiflora root decreases lipid accumulation through the induction of lipolysis and thermogenesis via AMPK activation in 3T3-L1 cells [J].

Choi, Jeong Won ;

Choi, Hyeok Jin ;

Ryu, Gwang Hyeon ;

Lee, Jae Won ;

Beak, Jueng Kyu ;

Koh, Eun Jeong ;

Jeong, Jin Boo .

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2023, 52 (02)

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