Imaging in the diagnosis and management of fibrosing interstitial lung diseases

被引:6
作者
Lederer, Christoph [1 ,2 ]
Storman, Monika [3 ]
Tarnoki, Adam Domonkos [4 ,5 ]
Tarnoki, David Laszlo [4 ,5 ,6 ]
Margaritopoulos, George A. [7 ,8 ]
Prosch, Helmut [9 ]
机构
[1] Univ Hosp Heidelberg, Ctr Interstitial & Rare Lung Dis, Pneumol, Thoraxklin Heidelberg, Heidelberg, Germany
[2] German Ctr Lung Res DZL, Heidelberg, Germany
[3] Med Univ Warsaw, Dept Internal Med Pulm Dis & Allergy, Warsaw, Poland
[4] Semmelweis Univ, Med Imaging Ctr, Budapest, Hungary
[5] Natl Inst Oncol, Oncol Imaging & Invas Diagnost Ctr, Dept Radiol, Budapest, Hungary
[6] Natl Inst Oncol, Natl Tumor Biol Lab, Budapest, Hungary
[7] G Papanikolaou Univ Hosp, ILD Unit, Saloniki, Greece
[8] Imperial Coll London, Natl Heart & Lung Inst, London, England
[9] Med Univ Vienna, Dept Biomed Imaging & Image guided Therapy, Vienna, Austria
关键词
IDIOPATHIC PULMONARY-FIBROSIS; CHRONIC HYPERSENSITIVITY PNEUMONITIS; RESPIRATORY-DISTRESS-SYNDROME; THIN-SECTION CT; COMPUTED-TOMOGRAPHY; FLEISCHNER-SOCIETY; FUNCTION INDEXES; COVID-19; PATTERN; FEATURES;
D O I
10.1183/20734735.0006-2024
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
High -resolution computed tomography (HRCT) plays a pivotal role in the diagnosis and management of interstitial lung diseases (ILDs), particularly given the approval of antifibrotic agents for conditions like idiopathic pulmonary fibrosis and progressive pulmonary fibrosis. Diagnosing fibrotic pulmonary disorders through HRCT involves a detailed and methodical examination. The identification of specific lung tissue changes, including ground -glass opacities and reticulation, along with signs of fibrosis like honeycombing, traction bronchiectasis and lung volume loss, establishes clear HRCT patterns indicative of various ILDs. The reliability of these patterns in predicting pathological conditions depends largely on the clinical context. For instance, when a usual interstitial pneumonia pattern is present, the predictive value of this diagnosis is so high that a lung biopsy is considered to be redundant. This review intends to delineate the HRCT signs of fibrosis, elucidate the specific radiological patterns of fibrotic lung diseases, and identify the clinical circumstances under which these patterns emerge. Additionally, we introduce and discuss novel imaging techniques that hold promise for the diagnosis, screening and early detection of ILDs.
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页数:17
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