Subsequent Renal Cancer Among Childhood Cancer Survivors: Analysis of Surveillance, Epidemiology, and End Results

被引:0
|
作者
Bell, Anthony [1 ]
Rangaswami, Arun [2 ]
Murphy, Patricia [2 ]
Meng, Max [3 ]
Raphael, Robert [2 ]
Wu, Natalie [2 ]
Goldsby, Robert [2 ]
机构
[1] UCSF Benioff Childrens Hosp, Dept Pediat, San Francisco, CA USA
[2] UCSF Benioff Childrens Hosp, Dept Pediat Hematol Oncol, San Francisco, CA USA
[3] UCSF Benioff Childrens Hosp, Dept Urol, San Francisco, CA USA
关键词
survivors; subsequent cancer; renal cancer; SECONDARY MALIGNANT NEOPLASMS; LONG-TERM SURVIVORS; CELL CARCINOMA; YOUNG-ADULTS; 5-YEAR SURVIVORS; BREAST-CANCER; KIDNEY CANCER; RISK; ADOLESCENTS; RADIATION;
D O I
10.1097/MPH.0000000000002910
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Renal cancer, although still rare among individuals under 45 years of age, is on the rise in the general population. The risk and timing of subsequent renal cancer in survivors of childhood cancer is not well established. Using the SEER registry, we reported the incidence of subsequent malignant renal neoplasms after treatment for primary malignancy diagnosed under 20 years of age. We evaluated clinical characteristics, standardized incidence ratio (SIR), and Kaplan-Meier survival estimates. Fifty-three survivors developed subsequent renal cancer (54 total cases). Of these, 54.7% were female, 88.7% were white, and 13.2% were Hispanic. Mean ages at primary malignancy and subsequent renal cancer were 10.1 and 31.1 years, respectively. Forty-seven cases were second cancers, 6 were third, and 1 was fourth. For survivors of childhood cancer, the overall SIR for renal cancer was 4.52 (95% CI: 3.39-5.89). The 5-year overall survival rate after development of subsequent renal cancer was 73% (95% CI: 58%-83%). Renal cancer occurs 4.5 times more frequently in childhood cancer survivors than in the general population, necessitating long-term care considerations.
引用
收藏
页码:e387 / e392
页数:6
相关论文
共 50 条
  • [1] Subsequent neoplasms in childhood cancer survivors
    Zichova, Andrea
    Eckschlager, Tomas
    Ganevova, Marta
    Malinova, Bela
    Luks, Ales
    Kruseova, Jarmila
    CANCER EPIDEMIOLOGY, 2020, 68
  • [2] Risk of second benign brain tumors among cancer survivors in the surveillance, epidemiology, and end results program
    Kutsenko, Alina
    de Gonzalez, Amy Berrington
    Curtis, Rochelle E.
    Rajaraman, Preetha
    CANCER CAUSES & CONTROL, 2014, 25 (06) : 659 - 668
  • [3] Skin Cancer Surveillance Behaviors Among Childhood Cancer Survivors
    Stapleton, Jerod L.
    Tatum, Kristina L.
    Devine, Katie A.
    Stephens, Sue
    Masterson, Margaret
    Baig, Amna
    Hudson, Shawna V.
    Coups, Elliot J.
    PEDIATRIC BLOOD & CANCER, 2016, 63 (03) : 554 - 557
  • [4] Risk of subsequent gastrointestinal cancer among childhood cancer survivors: A systematic review
    Teepen, Jop C.
    de Vroom, Suzanne L.
    van Leeuwen, Flora E.
    Tissing, Wim J.
    Kremer, Leontien C.
    Ronckers, Cecile M.
    CANCER TREATMENT REVIEWS, 2016, 43 : 92 - 103
  • [5] Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review
    Bowers, Daniel C.
    Nathan, Paul C.
    Constine, Louis
    Woodman, Catherine
    Bhatia, Smita
    Keller, Karen
    Bashore, Lisa
    LANCET ONCOLOGY, 2013, 14 (08) : E321 - E328
  • [6] Esophageal Cancer: An Updated Surveillance Epidemiology and End Results Database Analysis
    Then, Eric Omar
    Lopez, Michell
    Saleem, Saad
    Gayam, Vijay
    Sunkara, Tagore
    Culliford, Andrea
    Gaduputi, Vinaya
    WORLD JOURNAL OF ONCOLOGY, 2020, 11 (02) : 55 - 64
  • [7] Subsequent Neoplasms in 5-Year Survivors of Childhood Cancer: The Childhood Cancer Survivor Study
    Friedman, Debra L.
    Whitton, John
    Leisenring, Wendy
    Mertens, Ann C.
    Hammond, Sue
    Stovall, Marilyn
    Donaldson, Sarah S.
    Meadows, Anna T.
    Robison, Leslie L.
    Neglia, Joseph P.
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2010, 102 (14): : 1083 - 1095
  • [8] Presentation and outcome of subsequent thyroid cancer among childhood cancer survivors compared to sporadic thyroid cancer: a matched national study
    Clement, Sarah C.
    Lebbink, Chantal A.
    Hesselink, Marielle S. Klein
    Teepen, Jop C.
    Links, Thera P.
    Ronckers, Cecile M.
    van Santen, Hanneke M.
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2020, 183 (02) : 169 - 180
  • [9] Risk factors for subsequent endocrine-related cancer in childhood cancer survivors
    Wijnen, M.
    van den Heuvel-Eibrink, M. M.
    Medici, M.
    Peeters, R. P.
    van der Lely, A. J.
    Neggers, S. J. C. M. M.
    ENDOCRINE-RELATED CANCER, 2016, 23 (06) : R299 - R321
  • [10] Conditional Survival in Pediatric Malignancies: Analysis of Data From the Childhood Cancer Survivor Study and the Surveillance, Epidemiology, and End Results Program
    Mertens, Ann C.
    Yong, Jian
    Dietz, Andrew C.
    Kreiter, Erin
    Yasui, Yutaka
    Bleyer, Archie
    Armstrong, Gregory T.
    Robison, Leslie L.
    Wasilewski-Masker, Karen
    CANCER, 2015, 121 (07) : 1108 - 1117