Advancements in medical treatment for pancreatic neuroendocrine tumors: A beacon of hope

被引：3

作者：

Giri, Somdatta ^{[1
]}

Sahoo, Jayaprakash ^{[1
]}

机构：

[1] Jawaharlal Inst Postgrad Med Educ & Res, Dept Endocrinol & Metab, JIPMER Campus, Pondicherry 605006, India

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2024年 / 30卷 / 12期

关键词：

Pancreatic neuroendocrine tumor; Medical management; Somatostatin analog; Immunotherapy; Everolimus; EVEROLIMUS; EFFICACY;

D O I：

10.3748/wjg.v30.i12.1670

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

This editorial highlights the remarkable advancements in medical treatment strategies for pancreatic neuroendocrine tumors (pan-NETs), emphasizing tailored approaches for specific subtypes. Cytoreductive surgery and somatostatin analogs (SSAs) play pivotal roles in managing tumors, while palliative options such as molecular targeted therapy, peptide receptor radionuclide therapy, and chemotherapy are reserved for SSA-refractory patients. Gastrinomas, insulinomas, glucagonomas, carcinoid tumors and VIPomas necessitate distinct thera-peutic strategies. Understanding the genetic basis of pan-NETs and exploring immunotherapies could lead to promising avenues for future research. This review underscores the evolving landscape of pan-NET treatment, offering renewed hope and improved outcomes for patients facing this complex disease.

引用

页码：1670 / 1675

页数：7

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