Prediction of Mortality and Heart Failure Hospitalization After Transcatheter Tricuspid Valve Interventions Validation of TRISCORE

被引:15
作者
Adamo, Marianna [56 ,1 ]
Russo, Giulio [2 ]
Pagnesi, Matteo [1 ]
Pancaldi, Edoardo [1 ]
Alessandrini, Hannes [3 ]
Andreas, Martin [4 ]
Badano, Luigi P. [5 ,6 ]
Braun, Daniel [7 ]
Connelly, Kim A. [8 ]
Denti, Paolo [9 ,10 ]
Estevez-Loureiro, Rodrigo [11 ]
Fam, Neil [8 ]
Gavazzoni, Mara [5 ,6 ]
Hahn, Rebecca T. [12 ]
Harr, Claudia [3 ]
Hausleiter, Joerg [7 ]
Himbert, Dominique [13 ]
Kalbacher, Daniel [14 ]
Ho, Edwin [15 ]
Latib, Azeem [15 ]
Lubos, Edith [14 ]
Ludwig, Sebastian [14 ]
Lupi, Laura
Lurz, Philipp [16 ]
Monivas, Vanessa [17 ]
Nickenig, Georg [18 ]
Pedicino, Daniela [19 ,20 ]
Pedrazzini, Giovanni [21 ,22 ]
Pozzoli, Alberto [23 ]
Marafon, Denise Pires [24 ]
Pastorino, Roberta [24 ,25 ]
Praz, Fabien [26 ]
Rodes-Cabau, Joseph [27 ]
Besler, Christian [16 ]
Schoeber, Anne Rebecca [16 ]
Schofer, Joachim [5 ]
Scotti, Andrea [15 ]
Piayda, Kerstin [28 ]
Sievert, Horst [28 ]
Tang, Gilbert H. L. [16 ,29 ]
Sticchi, Alessandro [16 ,30 ]
Messika-Zeitoun, David [31 ]
Thiele, Holger
Schloetter, Florian
Bardeleben, Ralph Stephan von [32 ]
Webb, John [33 ]
Dreyfus, Julien [34 ]
Windecker, Stephan
Leon, Martin [12 ]
Maisano, Francesco
机构
[1] Univ Brescia, Inst Cardiol, Dept Med & Surg Specialties Radiol Sci & Publ Hlt, Brescia, Italy
[2] Univ Rome, Dept Biomed & Prevent, Cardiol Unit, Policlin Tor Vergata, Rome, Italy
[3] Asklepios Clin Sankt Georg, Dept Cardiol, Hamburg, Germany
[4] Med Univ Vienna, Dept Cardiac Surg, Vienna, Austria
[5] Univ Milano Bicocca, Dept Med & Surg, Milan, Italy
[6] Dept Cardiol, Auxol IRCCS, Milan, Italy
[7] Univ Hosp Munich Grosshadern, Med Clin & Polyclin 1, Munich, Germany
[8] St Michaels Hosp, Toronto Heart Ctr, Div Cardiol, Toronto, ON, Canada
[9] San Raffaele Univ Hosp, Div Vasc Surg, I-20100 Milan, Italy
[10] San Raffaele Univ Hosp, Dept Cardiac Surg, Milan, Italy
[11] Univ Hosp Alvaro Cunqueiro, Intervent Cardiol Clin, Vigo, Spain
[12] Columbia Univ, New York Presbyterian Hosp, Div Cardiol, Med Ctr, New York, NY USA
[13] Hop Xavier Bichat, Div Cardiol, Paris, France
[14] Univ Heart & Vasc Ctr, Dept Cardiol, Hamburg, Germany
[15] Montefiore Med Ctr, Div Cardiol, New York, NY USA
[16] Univ Leipzig, Leipzig Heart Ctr, Leipzig, Germany
[17] Puerta Hierro Univ Hosp, Div Cardiol, Madrid, Spain
[18] Univ Bonn, Heart Ctr, Bonn, Germany
[19] Fdn Policlin Univ A Gemelli IRCSS, Rome, Italy
[20] Univ Cattolica Sacro Cuore, Rome, Italy
[21] Ente Osped Cantonale EOC, Cardioctr Ticino Inst, Div Cardiol, Lugano, Switzerland
[22] Univ Svizzera Italiana, Biomed Fac, Lugano, Switzerland
[23] Cardioctr Ticino Inst, Div Cardiac Surg, EOC, Lugano, Switzerland
[24] Univ Dept Life Sci & Publ Hlth, Univ Cattolica Sacro Cuore, Sect Hyg, Rome, Italy
[25] Fdn Policlin Univ A Gemelli IRCCS, Dept Woman & Child Hlth & Publ Hlth, Publ Hlth Area, Rome, Italy
[26] Bern Univ Hosp, Cardiovasc Ctr, Dept Cardiol, Inselspital, Bern, Switzerland
[27] Laval Univ, Quebec Heart & Lung Inst, Quebec City, PQ, Canada
[28] Cardiovasc Ctr Frankfurt CVC, Frankfurt, Germany
[29] Mt Sinai Hlth Syst, Dept Cardiovasc Surg, New York, NY USA
[30] Humanitas Res Hosp, Intervent Cardiol, Rozzano Milanese, Italy
[31] Univ Ottawa Heart Inst, Dept Cardiol, Ottawa, ON, Canada
[32] Univ Med Ctr Mainz, Ctr Cardiol, Mainz, Germany
[33] St Paul Hosp, Vancouver, BC, Canada
[34] Ctr Cardiol Nord, Dept Cardiol, St Denis, France
[35] HerzZentrum Hirslanden, Zurich, Switzerland
关键词
risk model; transcatheter tricuspid valve intervention; tricuspid regurgitation; REGURGITATION; REPAIR; OUTCOMES; SOCIETY;
D O I
10.1016/j.jcin.2024.02.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Data on the prognostic role of the TRI -SCORE in patients undergoing transcatheter tricuspid valve intervention (TTVI) are limited. OBJECTIVES The aim of this study was to evaluate the performance of the TRI -SCORE in predicting outcomes of patients undergoing TTVI. METHODS TriValve (Transcatheter Tricuspid Valve Therapies) is a large multicenter multinational registry including patients undergoing TTVI. The TRI -SCORE isa risk model recently proposed to predict in -hospital mortality after tricuspid valve surgery. The TriValve population was strati fied based on the TRI -SCORE tertiles. The outcomes of interest were allcause death and all -cause death or heart failure hospitalization. Procedural complications and changes in NYHA functional class were also reported. RESULTS Among the 634 patients included, 223 patients (35.2%) had a TRI -SCORE between 0 and 5, 221 (34.8%) had 6 or 7, and 190 (30%) had >= 8 points. Postprocedural blood transfusion, acute kidney injury, new atrial fibrillation, and in -hospital mortality were more frequent in the highest TRI -SCORE tertile. Postprocedure length of stay increased with a TRI -SCORE increase. A TRI -SCORE >= 8 was associated with an increased risk of 30-day all -cause mortality and all -cause mortality and the composite endpoint assessed at a median follow-up of 186 days (OR: 3.00; 95% CI: 1.38-6.55; HR: 2.17; 95% CI: 1.78-4.13; HR: 2.08, 95% CI: 1.57-2.74, respectively) even after adjustment for procedural success and EuroSCORE II or Society of Thoracic Surgeons Predicted Risk of Mortality. The NYHA functional class improved across all TRI -SCORE values. CONCLUSIONS In the TriValve registry, the TRI -SCORE has a suboptimal performance in predicting clinical outcomes. However, a TRISCORE >= 8 is associated with an increased risk of clinical events and a lack of prognostic bene fit after successful TTVI. (J Am Coll Cardiol Intv 2024;17:859 -870) (c) 2024 by the American College of Cardiology Foundation.
引用
收藏
页码:859 / 870
页数:12
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