Major depressive disorder after heart transplantation with partial response to antidepressant therapy and remission with aripiprazole augmentation: A case report

被引：0

作者：

Nakamura, Toshinori ^{[1
]}

Kuraishi, Yuta ^{[1
]}

Ohya, Dai ^{[1
]}

Kimura, Kazuhiro ^{[2
]}

Sasayama, Daimei ^{[1
]}

Washizuka, Shinsuke ^{[1
]}

机构：

[1] Shinshu Univ, Sch Med, Dept Psychiat, 3-1-1 Asahi, Matsumoto, Nagano 3908621, Japan

[2] Shinshu Univ, Sch Med, Dept Cardiovasc Med, Matsumoto, Nagano, Japan

来源：

NEUROPSYCHOPHARMACOLOGY REPORTS | 2024年 / 44卷 / 03期

关键词：

antidepressant; antipsychotics; aripiprazole; depression; heart transplant; DOUBLE-BLIND; SAFETY;

D O I：

10.1002/npr2.12463

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The incidence of major depressive disorder (MDD) after heart transplantation is high; however, there are no reports on treatment options when antidepressant therapy fails to improve the condition. We herein report on the case of a woman with MDD after heart transplantation who partially improved with antidepressant treatment but continued to have a loss of appetite. Augmentation treatment with aripiprazole improved her appetite, and her MDD went into remission. When antidepressant treatment is not sufficiently effective for MDD after heart transplantation, augmentation treatment with antipsychotics, such as aripiprazole, should be considered. A woman diagnosed with major depressive disorder (MDD) following a heart transplant experienced partial improvement with antidepressant treatment but continued to suffer from loss of appetite. Augmentation treatment with aripiprazole improved her appetite, and her MDD went into remission. When antidepressant treatment alone is not sufficiently effective for post-heart transplantation MDD, augmentation treatment with antipsychotics, such as aripiprazole, should be considered.image

引用

页码：569 / 571

页数：3