Cardiorenal syndrome: Plasmonic biosensors

被引：4

作者：

Rezabakhsh, Aysa ^{[1
]}

Fathi, Farzaneh ^{[2
]}

Habtemariam, Solomon ^{[3
]}

Ahmadian, Elham ^{[4
]}

机构：

[1] Tabriz Univ Med Sci, Cardiovasc Res Ctr, Tabriz, Iran

[2] Ardabil Univ Med Sci, Pharmaceut Sci Res Ctr, Ardebil, Iran

[3] Pharmacognosy Res & Herbal Anal Serv UK, Cent Ave, Chatham ME4 4TB, England

[4] Tabriz Univ Med Sci, Kidney Res Ctr, Tabriz, Iran

来源：

CLINICA CHIMICA ACTA | 2024年 / 562卷

关键词：

B -type natriuretic peptide; Cardiorenal syndrome; Myocardial infarction; Neutrophil gelatinase-associated lipocalin; Surface Plasmon Resonance; ACUTE KIDNEY INJURY; DECOMPENSATED HEART-FAILURE; ELEVATION MYOCARDIAL-INFARCTION; GELATINASE-ASSOCIATED LIPOCALIN; BRAIN NATRIURETIC PEPTIDE; SYNDROME TYPE-1; NT-PROBNP; CONSENSUS CONFERENCE; RENAL-FUNCTION; RESONANCE;

D O I：

10.1016/j.cca.2024.119870

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Cardiorenal syndrome (CRS) is defined as a broad spectrum of conditions encompassing both the heart and kidneys in which acute or chronic heart disorder may induce acute or chronic tubular injury in the kidneys and vice versa. Early diagnosis allows timely intervention and attenuates disease progression. Two well-established biomarkers, neutrophil gelatinase-associated lipocalin (NGAL) and brain (B-type) natriuretic peptide (BNP), are reflective of impaired cardiac and kidney function associated with poor prognosis in various cardiac disorders, including heart failure and coronary artery disease. Given the ongoing contribution of CRS to the high morbidity and mortality post-MI, early risk stratification and preventive measures are highly significant. In this review, we examine Surface Plasmon Resonance (SPR) optical biosensors for detection of these biomarkers and discuss potential implications of this highly sensitive and specific technology in CRS detection, treatment and outcomes.

引用

页数：12

共 99 条

[61] Cardiorenal Syndrome in Acute Heart Failure: Revisiting Paradigms [J].