Living Donor Intestinal Transplantation

ITx, both from living and deceased donors, continues to evolve, mirroring the everchanging nature of medical care for individuals with short gut syndrome. Although advancements in medical treatment prolonged survival without undergoing transplantation, severe complications persist. Consideration should be given to LDIT at an early stage of the patient evaluation. Moreover, LDIT notably demonstrates significant immunologic advantages which are immediately apparent in case of identical twins or HLA-identical siblings. In such cases, the elective nature of the procedure allows better immunologic risk stratification and offers a substantial benefit. In conclusion, the importance of donor selection and recipient evaluation cannot be emphasized enough. Ensuring the safety and well-being of living donors remains paramount, while meticulously assessing recipients is essential to achieving the best possible outcomes. With improvements in the medical and surgical management, a multidisciplinary approach is necessary to meet the unique needs of each patient and to offer the best possible outcomes to donor and recipients if consideration is given to LDIT.