Minimal Change Nephrotic Syndrome Secondary to Methotrexate-associated Hodgkin Lymphoma

被引：0

作者：

Iimori, Misa ^{[1
]}

Sonomura, Kazuhiro ^{[2
]}

Ueyama, Yuichi ^{[1
]}

Oobayashi, Yuki ^{[1
]}

Adachi, Hiroya ^{[2
]}

Nakayama, Mayuka ^{[1
]}

机构：

[1] Japanese Red Cross Kyoto Daiichi Hosp, Dept Pathol, Kyoto, Japan

[2] Matsushita Mem Hosp, Dept Rehabil, Moriguchi, Japan

来源：

INTERNAL MEDICINE | 2024年 / 63卷 / 12期

关键词：

minimal change nephrotic syndrome; methotrexate; Hodgkin lymphoma; T lymphocyte dysfunction; rheumatoid arthritis; BARR-VIRUS INFECTION; RHEUMATOID-ARTHRITIS;

D O I：

10.2169/internalmedicine.2572-23

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The patient was a 64-year-old man who had been receiving methotrexate (MTX) for rheumatoid arthritis for 8 years. Computed tomography (CT) obtained one month prior to admission revealed numerous enlarged lymph nodes. Lower leg edema appeared two weeks prior to admission. Severe proteinuria was confirmed, and the patient was admitted. A renal biopsy revealed minimal changes in glomeruli. CT on day 14 revealed shrinking lymph nodes, and the patient was diagnosed with Hodgkin lymphoma by a neck lymph node biopsy. This is the first report of secondary minimal change nephrotic syndrome caused by an MTX-associated lymphoproliferative disorder.

引用

页码：1771 / 1776

页数：6

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