Investigating the Impacts of Diet, Supplementation, Microbiota, Gut-Brain Axis on Schizophrenia: A Narrative Review

被引:2
作者
Zajkowska, Izabela [1 ]
Niczyporuk, Patrycja [1 ]
Urbaniak, Agata [1 ]
Tomaszek, Natalia [1 ]
Modzelewski, Stefan [1 ]
Waszkiewicz, Napoleon [1 ]
机构
[1] Med Univ Bialystok, Dept Psychiat, Pl Wolodyjowskiego 2, PL-15272 Bialystok, Poland
关键词
gut-brain axis; diet; schizophrenia; supplementation; microbiota; eating habits; neuroleptics; POLYUNSATURATED FATTY-ACIDS; N-ACETYL CYSTEINE; PLACEBO-CONTROLLED TRIAL; IRRITABLE-BOWEL-SYNDROME; WITHANIA-SOMNIFERA; GINKGO-BILOBA; DOUBLE-BLIND; VITAMIN-D; IMMUNE ACTIVATION; HELICOBACTER-PYLORI;
D O I
10.3390/nu16142228
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Schizophrenia is a disease with a complex etiology that significantly impairs the functioning of patients. In recent years, there has been increasing focus on the importance of the gut microbiota in the context of the gut-brain axis. In our study, we analyzed data on the gut-brain axis in relation to schizophrenia, as well as the impacts of eating habits, the use of various supplements, and diets on schizophrenia. Additionally, the study investigated the impact of antipsychotics on the development of metabolic disorders, such as diabetes, dyslipidemia, and obesity. There may be significant clinical benefits to be gained from therapies supported by supplements such as omega-3 fatty acids, B vitamins, and probiotics. The results suggest the need for a holistic approach to the treatment of schizophrenia, incorporating both drug therapy and dietary interventions.
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页数:36
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