Interleukin-23 p19 and Interleukin-12 p40, Head-to-Head, against Gut Inflammation

被引：0

作者：

Abraham, Clara ^{[1
]}

机构：

[1] Yale Univ, New Haven, CT 06520 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2024年 / 391卷 / 03期

关键词：

D O I：

10.1056/NEJMe2405452

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The interleukin-12 and interleukin-23 cytokines play a critical role in homeostasis and inflammation in the intestine and share various features, including a common p40 cytokine subunit, a common interleukin-12R beta 1 receptor subunit, and Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling molecules that communicate downstream functions(1,2) (

引用

页码：275 / 277

页数：3

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