Models of sepsis-induced acute kidney injury

被引:5
作者
Dong, Liang [1 ]
Xie, Yi-Ling [1 ]
Zhang, Ren-Tao [1 ]
Hu, Qiong-Ying [1 ]
机构
[1] Taizhou Univ, Taizhou Univ Hosp, Taizhou Cent Hosp, Sch Med,Dept Crit Care Med, Taizhou 318000, Zhejiang, Peoples R China
关键词
Sepsis; Acute kidney injury; Animal models; Kidney organoid models; Cell models; CECAL LIGATION; SEPTIC SHOCK; TIGHT JUNCTION; INFLAMMATORY RESPONSE; ANIMAL-MODELS; PUNCTURE; ORGANOIDS; DISEASE; GENERATION; EXPRESSION;
D O I
10.1016/j.lfs.2024.122873
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Sepsis-induced acute kidney injury (S-AKI) is one of the most serious life-threatening complications of sepsis. The pathogenesis of S-AKI is complex and there is no effective specific treatment. Therefore, it is crucial to choose suitable preclinical models that are highly similar to human S-AKI to study the pathogenesis and drug treatment. In this review, we summarized recent advances in the development models of S-AKI, providing reference for the reasonable selection of experimental models as basic research and drug development of S-AKI.
引用
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页数:8
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共 110 条
[1]   COMPLEMENT ACTIVATION IN HUMAN SEPSIS IS RELATED TO SEPSIS-INDUCED DISSEMINATED INTRAVASCULAR COAGULATION [J].
Abe, Tomohiro ;
Kubo, Keisuke ;
Izumoto, Shintaro ;
Shimazu, Shihoko ;
Goan, Atsushi ;
Tanaka, Tatsuya ;
Koroki, Takatoshi ;
Saito, Katsutoshi ;
Kawana, Ryo ;
Ochiai, Hidenobu .
SHOCK, 2020, 54 (02) :198-204
[2]   Can the Cecal Ligation and Puncture Model Be Repurposed To Better Inform Therapy in Human Sepsis? [J].
Alverdy, John C. ;
Keskey, Robert ;
Thewissen, Renee .
INFECTION AND IMMUNITY, 2020, 88 (09)
[3]   Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care [J].
Angus, DC ;
Linde-Zwirble, WT ;
Lidicker, J ;
Clermont, G ;
Carcillo, J ;
Pinsky, MR .
CRITICAL CARE MEDICINE, 2001, 29 (07) :1303-1310
[4]   Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy [J].
Bagshaw, Sean M. ;
Lapinsky, Stephen ;
Dial, Sandra ;
Arabi, Yaseen ;
Dodek, Peter ;
Wood, Gordon ;
Ellis, Paul ;
Guzman, Jorge ;
Marshall, John ;
Parrillo, Joseph E. ;
Skrobik, Yoanna ;
Kumar, Anand .
INTENSIVE CARE MEDICINE, 2009, 35 (05) :871-881
[5]   Sepsis-mediated renal dysfunction: Pathophysiology, biomarkers and role of phytoconstituents in its management [J].
Balkrishna, Acharya ;
Sinha, Sugandh ;
Kumar, Ashwani ;
Arya, Vedpriya ;
Gautam, Ajay Kumar ;
Valis, Martin ;
Kuca, Kamil ;
Kumar, Dinesh ;
Amarowicz, Ryszard .
BIOMEDICINE & PHARMACOTHERAPY, 2023, 165
[6]   Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors [J].
Bantounas, Ioannis ;
Ranjzad, Parisa ;
Tengku, Faris ;
Silajdzic, Edina ;
Forster, Duncan ;
Asselin, Marie-Claude ;
Lewis, Philip ;
Lennon, Rachel ;
Plagge, Antonius ;
Wang, Qi ;
Woolf, Adrian S. ;
Kimber, Susan J. .
STEM CELL REPORTS, 2018, 10 (03) :766-779
[7]   Acute kidney injury in sepsis [J].
Bellomo, Rinaldo ;
Kellum, John A. ;
Ronco, Claudio ;
Wald, Ron ;
Martensson, Johan ;
Maiden, Matthew ;
Bagshaw, Sean M. ;
Glassford, Neil J. ;
Lankadeva, Yugeesh ;
Vaara, Suvi T. ;
Schneider, Antoine .
INTENSIVE CARE MEDICINE, 2017, 43 (06) :816-828
[8]   Alkaline phosphatase: a potential biomarker for stroke and implications for treatment [J].
Brichacek, Allison L. ;
Brown, Candice M. .
METABOLIC BRAIN DISEASE, 2019, 34 (01) :3-19
[9]   Protecting the kidney in sepsis: resident macrophages to the rescue [J].
Burns, Kevin D. ;
Douvris, Adrianna .
KIDNEY INTERNATIONAL, 2023, 103 (03) :461-463
[10]   Protective effect of resin adsorption on septic plasma-induced tubular injury [J].
Cantaluppi, Vincenzo ;
Weber, Viktoria ;
Lauritano, Carola ;
Figliolini, Federico ;
Beltramo, Silvia ;
Biancone, Luigi ;
De Cal, Massimo ;
Cruz, Dinna ;
Ronco, Claudio ;
Segoloni, Giuseppe Paolo ;
Tetta, Ciro ;
Camussi, Giovanni .
CRITICAL CARE, 2010, 14 (01)