Influence of the COVID-19 Pandemic on Patients with Rectal Cancer

被引:2
作者
Speichinger, Fiona [1 ]
Berg, Ann-Kathrin [1 ]
Stoyanova, Ani [1 ]
Lauscher, Johannes Christian [1 ]
Kamphues, Carsten [2 ]
Beyer, Katharina [1 ]
Seifarth, Claudia [1 ]
Slavova, Nadia [1 ]
Schineis, Christian [1 ]
机构
[1] Charite Univ Med Berlin, Dept Gen & Visceral Surg, D-12203 Berlin, Germany
[2] Pk Klin Weissensee Berlin, Dept Gen & Visceral Surg, D-13086 Berlin, Germany
关键词
COVID-19; pandemic; SARS-CoV-2; rectum cancer; lockdown; COLORECTAL-CANCER; 1ST WAVE; IMPACT; CLASSIFICATION; GERMANY; STAGE;
D O I
10.3390/jcm13123568
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: The COVID-19 pandemic and its associated restrictions have resulted in delayed diagnoses across various tumor entities, including rectal cancer. Our hypothesis was based on the expectation of a reduced number of primary operations due to higher tumor stages compared to the control group. Methods: In a single-center retrospective study conducted from 1 March 2018 to 1 March 2022, we analyzed 120 patients with an initial diagnosis of rectal cancer. Among them, 65 patients were part of the control group (pre-COVID-19), while 55 patients were included in the study group (during the COVID-19 pandemic). We compared tumor stages, treatment methods, and complications, presenting data as absolute numbers or mean values. Results: Fewer primary tumor resections during the COVID-19 pandemic (p = 0.010), as well as a significantly lower overall number of tumor resections (p = 0.025) were seen compared to the control group. Twenty percent of patients in the COVID-19 group received their diagnosis during lockdown periods. These patients presented significantly higher tumor stages (T4b: 27.3% vs. 6.2%, p = 0.025) compared to the control group prior to the pandemic. In addition, more patients with angiolymphatic invasion (ALI) were identified in the COVID-19 group following neoadjuvant treatment compared to the control group (p = 0.027). No differences were noted between the groups regarding complications, stoma placement, or conversion rates. Conclusions: The COVID-19 pandemic, particularly during lockdown, appears to have contributed to delayed diagnoses, resulting in higher tumor stages and a decreased number of surgeries. The quality of rectal cancer treatment can be maintained under pandemic conditions.
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页数:12
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