Infective endocarditis: Clinical presentation, etiology, and early predictors of in-hospital case fatality

被引:5
作者
Pilmis, B. [1 ]
Mizrahi, A. [2 ]
Laincer, A. [2 ]
Couzigou, C. [1 ,3 ]
El Helali, N. [2 ]
Nguyen Van, J. -C. [2 ]
Abassade, P. [4 ]
Cador, R. [4 ]
Le Monnier, A. [2 ]
机构
[1] Grp Hosp Paris St Joseph, Equipe Mobile Microbiol Clin, 185 Rue Raymond Losserand, F-75014 Paris, France
[2] Grp Hosp Paris St Joseph, Lab Microbiol Clin & Dosage Antiinfect, 185 Rue Raymond Losserand, F-75014 Paris, France
[3] Grp Hosp Paris St Joseph, Equipe Operat Hyg, 185 Rue Raymond Losserand, F-75014 Paris, France
[4] Grp Hosp Paris St Joseph, Serv Cardiol, 185 Rue Raymond Losserand, F-75014 Paris, France
来源
MEDECINE ET MALADIES INFECTIEUSES | 2016年 / 46卷 / 01期
关键词
Infective endocarditis; Epidemiology; INTERNATIONAL-COLLABORATION; STAPHYLOCOCCUS-AUREUS; EMBOLIC EVENTS; DIAGNOSIS; SURGERY; IMPACT;
D O I
10.1016/j.medmal.2015.12.012
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Objective. - We aimed to assess the clinical presentation, microbial etiology and outcome of patients presenting with infective endocarditis (IE). Patients and methods. - We conducted a four-year retrospective study including all patients presenting with IE. Results. - We included 121 patients in the study. The median age was 74.8 years. Most patients had native valve M (57%). Staphylococcus aureus accounted for 24.8% of all IE. Surgery was indicated for 70 patients (57.9%) but actually performed in only 55 (44.7%). Factors associated with surgery were younger age (P = 0.002) and prosthetic valve IE (P = 0.001). Risk factors associated with in-hospital mortality were diabetes mellitus (OR = 3.17), chronic renal insufficiency (OR=6.62), and surgical indication (OR=3.49). Mortality of patients who underwent surgery was one sixth of that of patients with surgical indication who did not have the surgery (P < 0.001). (C) 2016 Published by Elsevier Masson SAS.
引用
收藏
页码:44 / 48
页数:5
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