Multiple myeloma complicated with light chain cast nephropathy with focal amyloidosis: A case report

被引：0
作者：
He, Yicao [1 ,2 ]
Hua, Zhijuan [1 ,2 ]
Tan, Hu [1 ,2 ]
Zhao, Congjuan [1 ,2 ]
Liu, Qiang [1 ,2 ]
Jia, Juan [1 ,2 ,3 ]
Gao, Yan [1 ,2 ,3 ]
机构：
[1] Hebei Univ, Affiliated Hosp, Div Nephrol, 212 Yuhua East Rd, Baoding 071000, Hebei, Peoples R China
[2] Hebei Univ, Coll Clin Med, Baoding, Hebei, Peoples R China
[3] Key Lab Bone Metab & Physiol Chron Kidney Dis Hebe, Baoding, Hebei, Peoples R China
来源：
NEPHROLOGY | 2024年 / 29卷 / 10期
关键词：
autologous stem cell transplantation; focal amyloidosis; light chain cast nephropathy; multiple myeloma;
D O I：
10.1111/nep.14315
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
This case report describes a rare and interesting case of a patient with multiple myeloma complicated with light chain (LC) cast nephropathy and focal amyloidosis. The patient presented with acute kidney injury, anaemia and bone lesions. The diagnosis was confirmed by bone marrow biopsy, serum and urine electrophoresis and kidney biopsy. The patient was treated with isazomil, pomalidomide and dexamethasone combination chemotherapy, followed by autologous stem cell transplantation. The patient achieved clinical remission, stable renal function and improved serum lambda free LC levels. This case highlights the challenges and advances in the diagnosis and treatment of this condition.
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页码：691 / 694
页数：4
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