The Clinical Significance and Application of Heart Rate Variability in Dialysis Patients: A Narrative Review

被引:1
作者
Jhen, Rong-Na [1 ]
Wang, Ping-Chen [2 ]
Chang, Yu-Ming [1 ]
Kao, Jsun-Liang [1 ]
Wu, Eric Chien-Hwa [3 ]
Shiao, Chih-Chung [1 ]
机构
[1] Camillian St Marys Hosp Luodong, Dept Internal Med, Div Nephrol, 160,Zhongzheng S Rd, Luodong Township 265, Yilan, Taiwan
[2] Camillian St Marys Hosp Luodong, Dept Med Res & Educ, 160,Zhongzheng S Rd, Luodong Township 265, Yilan, Taiwan
[3] Camillian St Marys Hosp Jiaoxi, Dept Internal Med, Div Nephrol, 129,Sec 4,Jiaoxi R, Jiaoxi Township 262, Yilan, Taiwan
关键词
autonomic nervous system; end-stage kidney disease; heart rate variability; dialysis; prediction; prognosis; SHORT-TERM; RISK STRATIFICATION; CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME; SPECTRAL-ANALYSIS; RENAL-FAILURE; DYSFUNCTION; MORTALITY; PREDICTS;
D O I
10.3390/biomedicines12071547
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Autonomic nervous system (ANS) dysfunction is prevalent in end-stage kidney disease (ESKD) patients, carrying significant risks for morbidity and mortality. Heart rate variability (HRV) is a simple and non-invasive method to evaluate ANS functions and predict prognoses in specific patient populations. Since there is a lack of a clear understanding of the clinical significance of HRV in predicting prognoses in ESKD patients, an updated review on this topic is urgently warranted. The clinical significance of HRV in dialysis patients includes its associations with metabolic syndrome, nutritional status, intradialytic hypotension, vascular access failure, major adverse cardiovascular events, and mortality. These findings underscore the essential role of the autonomic reserve, which might denote the elevation of ANS activity as a response to external stimulus. Patients with a higher level of sympathetic activity at the resting stage, but who are unable to adequately elevate their sympathetic activity under stress might be susceptible to a worse outcome in critical circumstances. Further applications of HRV include HRV biofeedback, risk classification, and real-time HRV monitoring. Overall, HRV is an optimal tool for predicting prognoses in dialysis patients. Further study is encouraged in order to gain a clearer understanding of the clinical significance and application of HRV, and thereby enhance the care of ESKD patients.
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页数:16
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