Falling From Laughing: Laughing Gas-Induced Subacute Combined Degeneration From Nitrous Oxide

被引：0

作者：

Rao, Abhinav K. ^{[1
]}

Syed, Fahim ^{[1
]}

Lee, Thomas J. ^{[2
]}

Umanzor, Gilberto U. ^{[1
]}

Bodle, Jeffrey ^{[3
]}

机构：

[1] Trident Med Ctr, Internal Med, Charleston, SC 29406 USA

[2] Rutgers Univ New Jersey Med Sch, Internal Med, Newark, NJ USA

[3] Trident Med Ctr, Neurol, Charleston, SC USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 06期

关键词：

nitrous oxide; neurology; subacute combined degeneration; nitrous oxide abuse; laughing gas;

D O I：

10.7759/cureus.62138

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Laughing gas is becoming increasingly popular as a recreational drug of choice, particularly among young adults. Nitrous oxide, the toxic component of laughing gas, can cause neuronal injury when used in high doses. Through multiple mechanisms, nitrous oxide leads to B12 depletion and subsequent demyelination, particularly in the spinal cord. Here, we present the case of a 27-year-old female who presented with ataxia and was found to have laughing gas-induced subacute combined degeneration from nitrous oxide. After aggressive vitamin B12 repletion and laughing gas cessation for three months, the patient improved.

引用

页数：6

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