Theoretical and numerical study of a skeletal muscle regeneration model with inflammatory response

被引:0
作者
Ruiz-Bolanos, Jesus I. [1 ]
Kojouharov, Hristo V. [2 ]
Solis, Francisco J. [1 ]
机构
[1] CIMAT, Guanajuato 36000, Gto, Mexico
[2] Univ Texas Arlington, Dept Math, Arlington, TX USA
关键词
Muscular regeneration model; computational analysis; inflammation; pro-inflammatory mediator; GRANULOCYTE APOPTOSIS; MATHEMATICAL-MODEL; MACROPHAGE PHAGOCYTOSIS; LIPID MEDIATORS; RESOLUTION; NEUTROPHIL; CHEMOTAXIS; FRIEND; SYSTEM; CELLS;
D O I
10.1080/00207160.2024.2362786
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
A mathematical model of skeletal muscle regeneration for immune-muscular cell interactions with a pro-inflammatory mediator is introduced and analyzed. The model is a multi-scale problem with discontinuities and numerically stiff. Thus, a nonstandard parametric stability analysis of the equilibria is carried out in order to investigate the potential muscular regeneration and the inflammation resolution.
引用
收藏
页码:636 / 652
页数:17
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