Murine model captures evolution of edema in experimental cerebral malaria

被引:0
作者
Taylor, Terrie E. [1 ,2 ]
机构
[1] Michigan State Univ, Coll Osteopath Med, Dept Osteopath Med Specialties, E Lansing, MI 48824 USA
[2] Kamuzu Univ Hlth Sci, Blantyre Malaria Project, Blantyre, Malawi
关键词
CHILDREN;
D O I
10.1016/j.pt.2024.05.008
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
A complex series of studies by Oelschlegel et al . in a murine model of cerebral malaria establishes a temporal sequence of events linking decreased venous efflux to impaired perfusion, edema, and neuroinflammation. The relevance to human cerebral malaria is discussed, including the heterogeneity recognized in recent investigations of cerebrovascular hemodynamics.
引用
收藏
页码:544 / 545
页数:2
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