Cell therapy for retinal disease

被引：6

作者：

Yalla, Goutham R. ^{[1
,2
]}

Kuriyan, Ajay E. ^{[1
]}

机构：

[1] Wills Eye Hosp & Res Inst, Mid Atlantic Retina, Philadelphia, PA USA

[2] Thomas Jefferson Univ, Sidney Kimmel Med Coll, Philadelphia, PA USA

来源：

CURRENT OPINION IN OPHTHALMOLOGY | 2024年 / 35卷 / 03期

关键词：

macular degeneration; retina; retinal dystrophy; stem cell; INTRAVITREAL INJECTION; VISION LOSS; STEM-CELLS; SECONDARY;

D O I：

10.1097/ICU.0000000000001034

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose of reviewThis review presents an update on completed stem cell therapy trials aimed at retinal diseases.Recent findingsIn recent years, several clinical trials have been conducted examining the safety and role of cell therapy in diseases, including age-related macular degeneration, Stargardt's macular dystrophy, and retinitis pigmentosa. Studies have utilized a variety of cell lines, modes of delivery, and immunosuppressive regimens. The prevalence of fraudulent cell therapy clinics poses threats to patients.SummaryClinical trials have begun to characterize the safety of cell therapy in retinal disease. While studies have described the potential benefits of cell therapy, larger studies powered to evaluate this efficacy are required to continue progressing toward preventing retinal disease. Nonapproved cell therapy clinics require regulation and patient education to avoid patient complications.

引用

页码：178 / 184

页数：7

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