Rescue SLAMF7 activity in exhausted natural killer cells: Novel challenges in the immunotherapy of multiple myeloma

被引:0
作者
Zingoni, Alessandra [1 ]
Cippitelli, Marco [1 ]
机构
[1] Sapienza Univ Rome, Dept Mol Med, Rome, Italy
来源
CLINICAL AND TRANSLATIONAL DISCOVERY | 2022年 / 2卷 / 04期
关键词
exhaustion; multiple myeloma; NK cells; SLAMF7; NK CELLS;
D O I
10.1002/ctd2.143
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页数:3
相关论文
共 12 条
[1]   Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function [J].
Cruz-Munoz, Mario-Ernesto ;
Dong, Zhongjun ;
Shi, Xiaochu ;
Zhang, Shaohua ;
Veillette, Andre .
NATURE IMMUNOLOGY, 2009, 10 (03) :297-305
[2]   Myeloma natural killer cells are exhausted and have impaired regulation of activation [J].
D'Souza, Criselle ;
Keam, Simon P. ;
Yeang, Han Xian Aw ;
Neeson, Michael ;
Richardson, Kelden ;
Hsu, Andy K. ;
Canfield, Rachael ;
Bezman, Natalie ;
Robbins, Michael ;
Quach, Hang ;
Ritchie, David S. ;
Harrison, Simon J. ;
Trapani, Joseph A. ;
Prince, H. Miles ;
Beavis, Paul A. ;
Darcy, Phillip K. ;
Neeson, Paul J. .
HAEMATOLOGICA, 2021, 106 (09) :2522-2526
[3]   Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells [J].
Gao, Yulong ;
Souza-Fonseca-Guimaraes, Fernando ;
Bald, Tobias ;
Ng, Susanna S. ;
Young, Arabella ;
Ngiow, Shin Foong ;
Rautela, Jai ;
Straube, Jasmin ;
Waddell, Nic ;
Blake, Stephen J. ;
Yan, Juming ;
Bartholin, Laurent ;
Lee, Jason S. ;
Vivier, Eric ;
Takeda, Kazuyoshi ;
Messaoudene, Meriem ;
Zitvogel-, Laurence ;
Teng, Michele W. L. ;
Belz, Gabrielle T. ;
Engwerda, Christian R. ;
Huntington, Nicholas D. ;
Nakamura, Kyohei ;
Hoelzel, Michael ;
Smyth, Mark J. .
NATURE IMMUNOLOGY, 2017, 18 (09) :1004-+
[4]  
Li X., 2022, Clin Transl Med
[5]   CD155/TIGIT signalling plays a vital role in the regulation of bone marrow mesenchymal stem cell-induced natural killer-cell exhaustion in multiple myeloma [J].
Liu, Zhao-Yun ;
Deng, Ling ;
Jia, Yue ;
Liu, Hui ;
Ding, Kai ;
Wang, Wei ;
Zhang, Hongkai ;
Fu, Rong .
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 12 (07)
[6]   Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes [J].
Mackay, Laura K. ;
Minnich, Martina ;
Kragten, Natasja A. M. ;
Liao, Yang ;
Nota, Benjamin ;
Seillet, Cyril ;
Zaid, Ali ;
Man, Kevin ;
Preston, Simon ;
Freestone, David ;
Braun, Asolina ;
Wynne-Jones, Erica ;
Behr, Felix M. ;
Stark, Regina ;
Pellicci, Daniel G. ;
Godfrey, Dale I. ;
Belz, Gabrielle T. ;
Pellegrini, Marc ;
Gebhardt, Thomas ;
Busslinger, Meinrad ;
Shi, Wei ;
Carbone, Francis R. ;
van Lier, Rene A. W. ;
Kallies, Axel ;
van Gisbergen, Klaas P. J. M. .
SCIENCE, 2016, 352 (6284) :459-463
[7]   Immunotherapy of multiple myeloma [J].
Minnie, Simone A. ;
Hill, Geoffrey R. .
JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (04) :1565-1575
[8]   Alterations of NK Cell Phenotype in the Disease Course of Multiple Myeloma [J].
Pazina, Tatiana ;
MacFarlane, Alexander W. ;
Bernabei, Luca ;
Dulaimi, Essel ;
Kotcher, Rebecca ;
Yam, Clinton ;
Bezman, Natalie A. ;
Robbins, Michael D. ;
Ross, Eric A. ;
Campbell, Kerry S. ;
Cohen, Adam D. .
CANCERS, 2021, 13 (02) :1-22
[9]   Enhanced SLAMF7 Homotypic Interactions by Elotuzumab Improves NK Cell Killing of Multiple Myeloma [J].
Pazina, Tatiana ;
James, Ashley M. ;
Colby, Kimberly B. ;
Yang, Yibin ;
Gale, Andrew ;
Jhatakia, Amy ;
Kearney, Alper Y. ;
Graziano, Robert F. ;
Bezman, Natalie A. ;
Robbins, Michael D. ;
Cohen, Adam D. ;
Campbell, Kerry S. .
CANCER IMMUNOLOGY RESEARCH, 2019, 7 (10) :1633-1646
[10]   The Transcription Factor ZnF683/hOBiT regulates human NK-cell Development [J].
Post, Mirte ;
Cuapio, Angelica ;
Osl, Markus ;
Lehmann, Dorit ;
Resch, Ulrike ;
Davies, David M. ;
Bilban, Martin ;
Schlechta, Bernhard ;
Eppel, Wolfgang ;
Nathwani, Amit ;
Stoiber, Dagmar ;
Spanholtz, Jan ;
Casanova, Emilio ;
Hofer, Erhard .
FRONTIERS IN IMMUNOLOGY, 2017, 8