Colon Cancer, Version 3.2024

被引：111

作者：

Benson III, Al B. ^{[1
]}

Venook, Alan P. ^{[2
]}

Adam, Mohamed ^{[2
]}

Chang, George ^{[3
]}

Chen, Yi-Jen ^{[4
]}

Ciombor, Kristen K. ^{[5
]}

Cohen, Stacey A. ^{[6
]}

Cooper, Harry S. ^{[7
]}

Deming, Dustin ^{[8
]}

Garrido-Laguna, Ignacio ^{[9
]}

Grem, Jean L. ^{[10
]}

Haste, Paul ^{[11
]}

Hecht, J. Randolph ^{[12
]}

Hoffe, Sarah ^{[13
]}

Hunt, Steven ^{[14
,15
]}

Hussan, Hisham ^{[16
]}

Johung, Kimberly L. ^{[17
]}

Joseph, Nora ^{[18
]}

Kirilcuk, Natalie ^{[19
]}

Krishnamurthi, Smitha ^{[20
,21
]}

Malla, Midhun ^{[22
]}

Maratt, Jennifer K. ^{[11
]}

Messersmith, Wells A. ^{[23
]}

Meyerhardt, Jeffrey ^{[24
]}

Miller, Eric D. ^{[25
,26
]}

Mulcahy, Mary F. ^{[1
]}

Nurkin, Steven ^{[27
]}

Overman, Michael J. ^{[3
]}

Parikh, Aparna ^{[28
]}

Patel, Hitendra ^{[29
]}

Pedersen, Katrina ^{[14
,15
]}

Saltz, Leonard ^{[30
]}

Schneider, Charles ^{[31
]}

Shibata, David ^{[32
]}

Shogan, Benjamin ^{[33
]}

Skibber, John M.

Sofocleous, Constantinos T.

Tavakkoli, Anna ^{[34
]}

Willett, Christopher G. ^{[35
]}

Wu, Christina ^{[36
]}

Gurski, Lisa A. ^{[37
]}

Snedeker, Jenna ^{[37
]}

Jones, Frankie ^{[37
]}

机构：

[1] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[2] UCSF, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[3] Univ Texas MD Anderson Canc Ctr, Houston, TX USA

[4] City Hope Natl Med Ctr, Natl Med Ctr, Duarte, CA USA

[5] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[6] Fred Hutchinson Canc Ctr, Seattle, WA USA

[7] Fox Chase Canc Ctr, Philadelphia, PA USA

[8] Univ Wisconsin, Carbone Canc Ctr, Madison, WI 53706 USA

[9] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA

[10] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[11] Indiana Univ, Melvin & Bren Simon Comprehens Canc Ctr, Bloomington, IN USA

[12] UCLA, Jonsson Comprehens Canc Ctr, Los Angeles, CA USA

[13] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[14] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA

[15] Washington Univ, Sch Med, St Louis, MO USA

[16] Univ Calif Davis, Comprehens Canc Ctr, Davis, CA USA

[17] Yale Canc Ctr, Smilow Canc Hosp, New Haven, CT USA

[18] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI USA

[19] Stanford Canc Inst, Stanford, CA USA

[20] Seidman Canc Ctr, Univ Hosp, Case Comprehens Canc Ctr, Cleveland, OH USA

[21] Cleveland Clin, Taussig Canc Inst, Cleveland, OH USA

[22] UAB, ONeal Comprehens Canc Ctr, Birmingham, AL USA

[23] Univ Colorado, Canc Ctr, Boulder, CO USA

[24] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[25] Ohio State Univ, James Canc Hosp, Comprehens Canc Ctr, Columbus, OH USA

[26] Solove Res Inst, Columbus, OH USA

[27] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA

[28] Mass Gen Canc Ctr, Boston, MA USA

[29] Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA USA

[30] Mem Sloan Kettering Canc Ctr, New York, NY USA

[31] Univ Penn, Abramson Canc Ctr, Philadelphia, PA USA

[32] Univ Tennessee, Hlth Sci Ctr, Knoxville, TN USA

[33] UChicago, Med Comprehens Canc Ctr, Chicago, IL USA

[34] UT Southwestern, Simmons Comprehens Canc Ctr, Dallas, TX USA

[35] Duke Canc Inst, Durham, NC USA

[36] Mayo Clin, Comprehens Canc Ctr, Phoenix, AZ USA

[37] Natl Comprehens Canc Network, Plymouth Meeting, PA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2024年 / 22卷 / 2D期

关键词：

METASTATIC COLORECTAL-CANCER; WILD-TYPE KRAS; CETUXIMAB PLUS IRINOTECAN; PHASE-III TRIAL; MONOCLONAL-ANTIBODY THERAPY; MISMATCH REPAIR-DEFICIENT; POSITIVE SOLID TUMORS; 1ST-LINE COMBINATION CHEMOTHERAPY; POSTPROGRESSION SURVIVAL-TIME; BEVACIZUMAB-CONTAINING ARMS;

D O I：

10.6004/jnccn.2024.0029

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. Management of disseminated metastatic CRC involves various active drugs, either in combination or as single agents. The choice of therapy based on consideration of the goals of therapy, the type and timing of prior therapy, the mutational pro file of the tumor, and the differing toxicity pro files of the constituent drugs. This manuscript summarizes the data supporting the systemic therapy options recommended for metastatic CRC in the NCCN Guidelines for Colon Cancer.

引用

页数：26

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