Long-term survival following medical management of Aspergillus endocarditis with dissemination as a consequence of steroid therapy in severe COVID-19 pneumonia

被引:0
作者
Kulirankal, Kiran G. [1 ]
Mary, Ann [2 ]
Moni, Merlin [1 ]
Pillai, Gopal S. [3 ]
Sathyapalan, Dipu T. [1 ]
机构
[1] Amrita Inst Med Sci, Dept Internal Med, Div Infect Dis, Kochi, India
[2] Amrita Inst Med Sci, Dept Internal Med, Kochi, India
[3] Amrita Inst Med Sci, Dept Ophthalmol, Kochi, India
关键词
COVID-19; Covid pneumonia; Infectious diseases; Aspergillus fumigatus; Fungal endocarditis; Disseminated Aspergillus; STRATEGIES;
D O I
10.1016/j.mmcr.2024.100638
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
A male in his 40's with no known comorbidities developed severe COVID-19 pneumonia and received a fourweek course of methylprednisolone. The patient subsequently developed disseminated Aspergillus endocarditis, manifesting as multiple organ involvement including the heart, eyes, and brain. Despite the poor prognosis generally associated with fungal endocarditis, the patient survived following aggressive medical management with a combination of liposomal amphotericin b and voriconazole therapy and is now doing well for over two years and is off antifungal therapy for a year.
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