Mechanisms and therapeutic potential of chinonin in nervous system diseases

被引：9
作者：
Hui, Zhang [1 ,4 ]
Wang, Lai-Fa [1 ]
Wang, Xue-Qin [1 ]
Ling, Deng [1 ,2 ]
He, Bin-Sheng [3 ,4 ]
Li, Jian-Ming [1 ,4 ]
机构：
[1] Changsha Med Univ, Hunan Prov Univ, Key Lab Fundamental & Clin Res Neurodegenerat Dis, Changsha 410219, Peoples R China
[2] Changsha Med Univ, Hunan Prov Key Lab Res & Dev Novel Pharmaceut Prep, Changsha 410219, Peoples R China
[3] Changsha Med Univ, Hunan Prov Key Lab TCM Agr Biogenom, Changsha 410219, Peoples R China
[4] Changsha Med Univ, Hunan Prov Univ, Key Lab Fundamental & Clin Res Funct Nucl Acid, Changsha 410219, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2024年 / 26卷 / 12期
关键词：
Chinonin; nervous system diseases; neurological function; neuroprotection; molecular mechanism; NF-KAPPA-B; NLRP3; INFLAMMASOME; ALZHEIMERS-DISEASE; OXIDATIVE STRESS; ASSISTED EXTRACTION; BRAIN-INJURY; MOUSE MODEL; MANGIFERIN; ACTIVATION; NEUROINFLAMMATION;
D O I：
10.1080/10286020.2024.2371040
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. "Chinonin" OR "Mangiferin" AND "Nervous system diseases" OR "Neuroprotection" was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study. [GRAPHICS] .
引用
收藏
页码：1405 / 1420
页数：16
相关论文
共 81 条
  • [1] Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome
    Afonina, Inna S.
    Zhong, Zhenyu
    Karin, Michael
    Beyaert, Rudi
    [J]. NATURE IMMUNOLOGY, 2017, 18 (08) : 861 - 869
  • [2] NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder
    Alcocer-Gomez, Elisabet
    de Miguel, Manuel
    Casas-Barquero, Nieves
    Nunez-Vasco, Jessica
    Antonio Sanchez-Alcazar, Jose
    Fernandez-Rodriguez, Ana
    Cordero, Mario D.
    [J]. BRAIN BEHAVIOR AND IMMUNITY, 2014, 36 : 111 - 117
  • [3] NF-κB: At the Borders of Autoimmunity and Inflammation
    Barnabei, Laura
    Laplantine, Emmanuel
    Mbongo, William
    Rieux-Laucat, Frederic
    Weil, Robert
    [J]. FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [4] Neuropharmacological effect of Mangiferin on brain cholinesterase and brain biogenic amines in the management of Alzheimer's disease
    Biradar, Siddaruda M.
    Joshi, Hanumanthachar
    Chheda, Tarak K.
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 683 (1-3) : 140 - 147
  • [5] Mangiferin from Pueraria tuberosa reduces inflammation via inactivation of NLRP3 inflammasome
    Bulugonda, Ramakrishna K.
    Kumar, Kotha Anil
    Gangappa, D.
    Beeda, Harshavardhan
    Philip, Gundala Harold
    Rao, Dowlathabad Muralidhara
    Faisal, Syed M.
    [J]. SCIENTIFIC REPORTS, 2017, 7
  • [6] Mangiferin inhibits hippocampal NLRP3 inflammasome and exerts antidepressant effects in a chronic mild stress mice model
    Cao, Changfu
    Su, Meiqing
    Zhou, Feng
    [J]. BEHAVIOURAL PHARMACOLOGY, 2017, 28 (05): : 356 - 364
  • [7] Chang C.Y., 2000, MOLECULES, V25, P2020
  • [8] Extraction of Flavonoids From Natural Sources Using Modern Techniques
    Chaves, Jaisa Oliveira
    de Souza, Mariana Correa
    da Silva, Laise Capelasso
    Lachos-Perez, Daniel
    Torres-Mayanga, Paulo Cesar
    Machado, Ana Paula da Fonseca
    Forster-Carneiro, Tania
    Vazquez-Espinosa, Mercedes
    Gonzalez-de-Peredo, Ana Velasco
    Barbero, Gerardo Fernandez
    Rostagno, Mauricio Ariel
    [J]. FRONTIERS IN CHEMISTRY, 2020, 8
  • [9] SIRT1/PGC-1α signaling activation by mangiferin attenuates cerebral hypoxia/reoxygenation injury in neuroblastoma cells
    Chen, Mengfan
    Wang, Zheng
    Zhou, Wenying
    Lu, Chenxi
    Ji, Ting
    Yang, Wenwen
    Jin, Zhenxiao
    Tian, Ye
    Lei, Wangrui
    Wu, Songdi
    Fu, Qi
    Wu, Zhen
    Wu, Xue
    Han, Mengzhen
    Fang, Minfeng
    Yang, Yang
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 907
  • [10] ACUTE TOXICITY, ANTIDEPRESSIVE AND MAO INHIBITORY ACTIVITY OF MANGIFERIN ISOLATED FROM HYPERICUM AUCHERI
    Dimitrov, Martin
    Nikolova, Irina
    Benbasat, Niko
    Kitanov, Gerasim
    Danchev, Nikolai
    [J]. BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, 2011, 25 (04) : 2668 - 2671
123456789