Mechanisms and therapeutic potential of chinonin in nervous system diseases

被引：8

作者：

Hui, Zhang ^{[1
,4
]}

Wang, Lai-Fa ^{[1
]}

Wang, Xue-Qin ^{[1
]}

Ling, Deng ^{[1
,2
]}

He, Bin-Sheng ^{[3
,4
]}

Li, Jian-Ming ^{[1
,4
]}

机构：

[1] Changsha Med Univ, Hunan Prov Univ, Key Lab Fundamental & Clin Res Neurodegenerat Dis, Changsha 410219, Peoples R China

[2] Changsha Med Univ, Hunan Prov Key Lab Res & Dev Novel Pharmaceut Prep, Changsha 410219, Peoples R China

[3] Changsha Med Univ, Hunan Prov Key Lab TCM Agr Biogenom, Changsha 410219, Peoples R China

[4] Changsha Med Univ, Hunan Prov Univ, Key Lab Fundamental & Clin Res Funct Nucl Acid, Changsha 410219, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2024年 / 26卷 / 12期

关键词：

Chinonin; nervous system diseases; neurological function; neuroprotection; molecular mechanism; NF-KAPPA-B; NLRP3; INFLAMMASOME; ALZHEIMERS-DISEASE; OXIDATIVE STRESS; ASSISTED EXTRACTION; BRAIN-INJURY; MOUSE MODEL; MANGIFERIN; ACTIVATION; NEUROINFLAMMATION;

D O I：

10.1080/10286020.2024.2371040

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. "Chinonin" OR "Mangiferin" AND "Nervous system diseases" OR "Neuroprotection" was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study. [GRAPHICS] .

引用

页码：1405 / 1420

页数：16

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