Development of novel low-cost readout electronics for large field-of-view gamma camera detectors

被引:1
|
作者
Radnia, Aram [1 ]
Alikhani, Amirhossein [1 ]
Teimourian, Behnoosh [1 ]
Nejad, Mahyar Yousef [1 ]
Farahani, Mohammad Hossein [1 ]
Pashaei, Fakhereh [2 ]
Rahmim, Arman [4 ,5 ,6 ]
Zaidi, Habib [7 ,8 ,9 ,10 ,11 ]
Ay, Mohammad Reza [1 ,3 ,11 ]
机构
[1] Univ Tehran Med Sci, Adv Med Technol & Equipment Inst AMTEI, Res Ctr Mol & Cellular Imaging RCMCI, Tehran, Iran
[2] Inst Res Educ & Treatment Canc, Tehran, Iran
[3] Univ Tehran Med Sci, Dept Med Phys & Biomed Engn, Tehran, Iran
[4] Univ British Columbia, Dept Radiol, Vancouver, BC, Canada
[5] Univ British Columbia, Dept Phys & Astron, Vancouver, BC, Canada
[6] BC Canc Res Inst, Dept Integrat Oncol, Vancouver, BC, Canada
[7] Geneva Univ Hosp, Div Nucl Med & Mol Imaging, CH-1211 Geneva, Switzerland
[8] Univ Groningen, Univ Med Ctr Groningen, Dept Nucl Med & Mol Imaging, Groningen, Netherlands
[9] Univ Southern Denmark, Dept Nucl Med, Odense, Denmark
[10] Obuda Univ, Univ Res & Innovat Ctr, Budapest, Hungary
[11] Geneva Univ Hosp, Div Nucl Med & Mol Imaging, Geneva, Switzerland
来源
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS | 2024年 / 121卷
关键词
Gamma camera; Square PMT; Readout electronics; NEMA NU 1-2018; MAXIMUM-LIKELIHOOD; SCINTILLATION;
D O I
10.1016/j.ejmp.2024.103357
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: Large scintillation crystals -based gamma cameras play a crucial role in nuclear medicine imaging. In this study, a large field -of -view (FOV) gamma detector consisting of 48 square PMTs developed using a new readout electronics, reducing 48 (6 x 8) analog signals to 14 (6 + 8) analog sums of each row and column, with reduced complexity and cost while preserving image quality. Methods: All 14 analog signals were converted to digital signals using AD9257 high-speed analog to digital (ADC) converters driven by the SPARTAN -6 family of field -programmable gate arrays (FPGA) in order to calculate the signal integrals. The positioning algorithm was based on the digital correlated signal enhancement (CSE) algorithm implemented in the acquisition software. The performance characteristics of the developed gamma camera were measured using the NEMA NU 1-2018 standards. Results: The measured energy resolution of the developed detector was 8.7 % at 140 keV, with an intrinsic spatial resolution of 3.9 mm. The uniformity was within 0.6 %, while the linearity was within 0.1 %. Conclusion: The performance evaluation demonstrated that the developed detector has suitable specifications for high -end nuclear medicine imaging.
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页数:6
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