Body mass index is a barrier to obesity treatment

被引：1

作者：

Chin, Geoffrey C. ^{[1
]}

Potter, Adam W. ^{[1
]}

Friedl, Karl E. ^{[2
]}

机构：

[1] United States US Army Res Inst Environm Med, Thermal & Mt Med Div, Natick, MA 01760 USA

[2] United States US Army Res Inst Environm Med, Off Sr Scientist, Natick, MA USA

来源：

FRONTIERS IN ENDOCRINOLOGY | 2024年 / 15卷

关键词：

body fat; body mass index; BMI; metabolic syndrome; obesity; WAIST CIRCUMFERENCE; METABOLIC SYNDROME; RISK; BMI; FAT;

D O I：

10.3389/fendo.2024.1444568

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The Food and Drug Administration's (FDA) obesity drug guidance is set on the basis of body mass index (BMI), with thresholds of either BMI >= 30 or BMI >= 27 kg/m2 with weight-related comorbidities. While BMI is associated with obesity-related health outcomes, there are known limitations to use as a direct measure of body fat or metabolic health, and the American Medical Association has highlighted limitations of BMI in assessing individual obesity risks. BMI thresholds impose a barrier to treatment. In a sample from the NHANES dataset (n=6,646 men and women), 36% of individuals with metabolic syndrome (MetS) may not be eligible for obesity pharmacotherapy. This analysis provides quantifiable justification for refinement of the BMI treatment criteria with a more holistic assessment of individual obesity-related disease risk.

引用

页数：5

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