Acoustically Enhanced Triboelectric Stethoscope for Ultrasensitive Cardiac Sounds Sensing and Disease Diagnosis

被引:36
作者
Hui, Xindan [1 ,2 ]
Tang, Lirong [1 ,2 ]
Zhang, Dewen [1 ]
Yan, Shanlin [1 ]
Li, Dongxiao [3 ]
Chen, Jie [4 ]
Wu, Fei [1 ]
Wang, Zhong Lin [5 ]
Guo, Hengyu [1 ,2 ]
机构
[1] Chongqing Univ, Coll Mech & Vehicle Engn, Chongqing 400044, Peoples R China
[2] Chongqing Univ, Sch Phys, Chongqing 400044, Peoples R China
[3] Natl Univ Singapore, Dept Elect & Comp Engn, Singapore 117583, Singapore
[4] Chongqing Normal Univ, Coll Phys & Elect Engn, Chongqing 401331, Peoples R China
[5] Chinese Acad Sci, Beijing Inst Nanoenergy & Nanosyst, Beijing 100083, Peoples R China
基金
中国国家自然科学基金;
关键词
cardiac disorder; electronic stethoscope; low-intensity cardiac signal; piezoelectric; triboelectric; NANOGENERATORS; SENSORS; SYSTEM;
D O I
10.1002/adma.202401508
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Electronic stethoscope used to detect cardiac sounds that contain essential clinical information is a primary tool for diagnosis of various cardiac disorders. However, the linear electromechanical constitutive relation makes conventional piezoelectric sensors rather ineffective to detect low-intensity, low-frequency heart acoustic signal without the assistance of complex filtering and amplification circuits. Herein, it is found that triboelectric sensor features superior advantages over piezoelectric one for microquantity sensing originated from the fast saturated constitutive characteristic. As a result, the triboelectric sensor shows ultrahigh sensitivity (1215 mV Pa-1) than the piezoelectric counterpart (21 mV Pa-1) in the sound pressure range of 50-80 dB under the same testing condition. By designing a trumpet-shaped auscultatory cavity with a power function cross-section to achieve acoustic energy converging and impedance matching, triboelectric stethoscope delivers 36 dB signal-to-noise ratio for human test (2.3 times of that for piezoelectric one). Further combining with machine learning, five cardiac states can be diagnosed at 97% accuracy. In general, the triboelectric sensor is distinctly unique in basic mechanism, provides a novel design concept for sensing micromechanical quantities, and presents significant potential for application in cardiac sounds sensing and disease diagnosis. This work systematically analyzes the electromechanical output characteristics between a contact-separation triboelectric nanogenerator and a piezoelectric generator and proposes that triboelectric sensor features superior advantages over piezoelectric one for microquantity sensing originates from the fast saturated constitutive characteristic. By designing a trumpet-shaped auscultatory cavity, triboelectric stethoscope delivers 36 dB signal-to-noise ratio for human test. image
引用
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页数:9
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