The Blood Virome: A new frontier in biomedical science

被引：2

作者：

Kandathil, Abraham J. ^{[1
]}

Thomas, David L. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA

来源：

BIOMEDICINE & PHARMACOTHERAPY | 2024年 / 175卷

关键词：

Blood; Virome; Human health; Eukaryotic viruses; Commensal; Metagenomic sequencing; GB-VIRUS-C; HEPATITIS-G VIRUS; HUMAN PEGIVIRUS 2; DNA; INFECTION; IDENTIFICATION; DISEASE; ASSOCIATION; METAGENOMICS; GENOMES;

D O I：

10.1016/j.biopha.2024.116608

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Recent advances in metagenomic testing opened a new window into the mammalian blood virome. Comprised of well-known viruses like human immunodeficiency virus, hepatitis C virus, and hepatitis B virus, the virome also includes many other eukaryotic viruses and phages whose medical significance, lifecycle, epidemiology, and impact on human health are less well known and thus regarded as commensals. This review synthesizes available information for the so-called commensal virome members that circulate in the blood of humans considering their restriction to and interaction with the human host, their natural history, and their impact on human health and physiology.

引用

页数：7

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