Safety and Tolerability of NIM-1324, an Oral, Once-daily LANCL2 Agonist, in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study in Normal Healthy Volunteers

被引:0
作者
Leber, Andrew [1 ]
Hontecillas, Raquel [1 ]
Juni, Nuria Tubau [1 ]
Bassaganya-Riera, Josep [1 ]
机构
[1] NIMML Inst, Blacksburg, VA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2337
引用
收藏
页码:4631 / 4632
页数:2
相关论文
共 50 条
[41]   Safety, tolerability, pharmacokinetics, and pharmacodynamics of SHR-2010, a novel anti-MASP-2 antibody, in healthy volunteers: a randomized, double-blind, placebo-controlled phase 1 study [J].
Lin, Pingping ;
Wang, Chenjing ;
Hu, Xiaotong ;
Fang, Lin ;
Lin, Hongda ;
Sun, Feifei ;
Huang, Rong ;
Ban, Rongxin ;
Feng, Sheng ;
Gao, Zhenyan ;
Shen, Kai ;
Cao, Yu .
EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2025, 34 (04) :339-348
[42]   A MULTIPLE-ONCE DAILY DOSE, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF THE PHARMACOKINETICS AND TOLERABILITY OF ABT-089, A NOVEL NEURONAL NICOTINIC RECEPTOR PARTIAL AGONIST, IN HEALTHY VOLUNTEERS [J].
Garimella, Tushar ;
Awni, Walid ;
Yan, Jun ;
Florian, Hana ;
Dutta, Sandeep .
JOURNAL OF CLINICAL PHARMACOLOGY, 2010, 50 (09) :1068-1068
[43]   A First-In-Human, Randomised, Double-Blind, Placebo-Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Ketamine in Healthy Volunteers [J].
Silman, Daniel ;
Gadelrab, Romayne ;
Qureshi, Mutahira ;
Stein, Hans ;
Mehta, Mitul ;
Carmelline, Pietro ;
Young, Allan ;
Reilly, Carmel ;
Duncan, Graeme ;
Juruena, Mario .
NEUROPSYCHOPHARMACOLOGY, 2024, 49 :155-155
[44]   Safety and tolerability of KarXT (xanomeline–trospium) in a phase 2, randomized, double-blind, placebo-controlled study in patients with schizophrenia [J].
Christoph U. Correll ;
Angel S. Angelov ;
Andrew C. Miller ;
Peter J. Weiden ;
Stephen K. Brannan .
Schizophrenia, 8
[45]   Safety and tolerability of twice-daily balsalazide tablets: Results of a phase 3, randomized, double-blind, placebo-controlled, multicenter study [J].
Pruitt, Ronald E. ;
Rosen, Alan A. ;
Wruble, Lawrence ;
Sedghi, Shahriar ;
Shepard, Roland D. ;
Mareya, Shadreck M. ;
Huang, Shirley ;
Shaw, Audrey L. ;
Forbes, William F. .
GASTROENTEROLOGY, 2008, 134 (04) :A494-A494
[46]   Randomized, Double-blind, Placebo-controlled Phase 1 Study Of Vwf-binding Aptamer, Bb-031: Safety, Tolerability, Pharmacokinetic And Pharmacodynamic Activity In Healthy Volunteers [J].
Nimjee, Shahid M. ;
Wheeler, Debra ;
Nelson, Stacy ;
Shea, Richard J. ;
Sullivan, Taegen ;
Mayer, Christina ;
Pavliv, Leo ;
Layzer, Juliana M. ;
Lickliter, Jason ;
Sullenger, Bruce ;
Campbell, Bruce ;
Becker, Richard C. .
STROKE, 2023, 54
[47]   Tolerability and efficacy of valerian/lemon balm in healthy volunteers (a double-blind, placebo-controlled, multicentre study) [J].
Cerny, A ;
Schmid, K .
FITOTERAPIA, 1999, 70 (03) :221-228
[48]   Once-daily Oral Aripiprazole for Treatment of Tics in Children and Adolescents with Tourette's Disorder: A Randomized, Double-blind, Placebo-controlled Trial [J].
Sallee, Floyd R. ;
Kohegyi, Eva ;
Zhao, Joan ;
McQuade, Robert ;
Cox, Kevin ;
Sanchez, Raymond ;
Nyilas, Margaretta ;
Carson, William ;
Kurlan, Roger .
NEUROPSYCHOPHARMACOLOGY, 2014, 39 :S378-S379
[49]   Safety, Tolerability and Pharmacokinetics of FAAH Inhibitor V158866: A Double-Blind, Randomised, Placebo-Controlled Phase I Study in Healthy Volunteers [J].
Pawsey S. ;
Wood M. ;
Browne H. ;
Donaldson K. ;
Christie M. ;
Warrington S. .
Drugs in R&D, 2016, 16 (2) :181-191
[50]   Efficacy and Safety of Once-Daily Dosing of Udenafil in the Treatment of Erectile Dysfunction: Results of a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial [J].
Zhao, Chen ;
Kim, Sae Woong ;
Yang, Dae Yul ;
Kim, Je Jong ;
Park, Nam Cheol ;
Lee, Sung Won ;
Paick, Jae Seung ;
Ahn, Tai Young ;
Min, Kweon Sik ;
Park, Kwangsung ;
Park, Jong Kwan .
EUROPEAN UROLOGY, 2011, 60 (02) :380-387