Modified Scaffolds With Magnetic Nanoparticles in Periodontal Tissue Regeneration

Nanomaterials have displayed vast potential across a spectrum of biomedical applications, particularly in recent studies aimed at optimizing traditional systems. Metal oxide nanoparticles, like Magnetic nanoparticles (MNPs), offer unique physicochemical properties ideal for biomedical applications, advancing diagnostics, therapies, tissue engineering and imaging technologies in medicine. Their notable features, such as high specific surface area and porous structure, render them versatile for myriad medical and biological uses. When combined with polymers, MNPs have found utility in nano-scale treatments targeting specific human ailments, encompassing drug delivery, tissue engineering, and wound care. This review focuses on summarizing the utilization of MNPs examining their structural attributes, magnetic properties, biocompatibility, and their role in scaffolding applications. Furthermore, within the dental domain, periodontitis presents substantial challenges, prompting research into regenerative therapies to foster the growth and specialization of key cell types crucial for effective disease management and tissue revitalization. Tissue engineering faces significant challenges today, notably in designing multifunctional materials that can concurrently fulfill various roles, particularly within dental applications. There remains a scarcity of scaffolds effective for regenerating periodontal tissue, highlighting a critical area for advancement. Addressing these challenges is crucial for enhancing the effectiveness and applicability of tissue engineering in dental regenerative therapies. image