The clinical diagnosis of Parkinson's disease

被引：21

作者：

Munhoz, Renato P. ^{[1
,2
,3
]}

Tumas, Vitor ^{[4
]}

Pedroso, Jose Luiz ^{[5
]}

Silveira-Moriyama, Laura ^{[6
,7
]}

机构：

[1] Univ Hlth Network, Toronto Western Hosp, Morton & Gloria Shulman Movement Disorders Ctr, Toronto, ON, Canada

[2] Edmond J Safra Program Parkinsons Dis, Toronto, ON, Canada

[3] Krembil Res Inst, Toronto, ON M5T 2S8, Canada

[4] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Neurociencias & Ciencias Comportamento, Ribeirao Preto, SP, Brazil

[5] Univ Fed Sao Paulo, Dept Neurol, Sao Paulo, SP, Brazil

[6] Univ Estadual Campinas, Campinas, SP, Brazil

[7] UCL Queen Sq Inst Neurol, London, England

来源：

ARQUIVOS DE NEURO-PSIQUIATRIA | 2024年 / 82卷 / 06期

关键词：

Parkinson Disease; Supranuclear Palsy; Progressive; Multiple System Atrophy; Atherosclerotic Parkinsonism; Secondary Parkinsonism; SLEEP BEHAVIOR DISORDER; PROGRESSIVE SUPRANUCLEAR PALSY; BODY-MASS INDEX; OLFACTORY DYSFUNCTION; LEWY BODY; NONMOTOR FEATURES; SUBSTANTIA-NIGRA; ONSET; IMPAIRMENT; DEPRESSION;

D O I：

10.1055/s-0043-177775

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

After more than 200 years since its initial description, the clinical diagnosis of Parkinson 's disease (PD) remains an often -challenging endeavor, with broad implications that are fundamental for clinical management. Despite major developments in understanding it 's pathogenesis, pathological landmarks, non-motor features and potential paraclinical clues, the most accepted diagnostic criteria remain solidly based on a combination of clinical signs. Here, we review this process, discussing its history, clinical criteria, differential diagnoses, ancillary diagnostic testing, and the role of nonmotor and pre-motor signs and symptoms.

引用

页数：10

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