Two Different Tumors and Lung Aspergilloma: An Uncommon Etiopathogenic Association

被引：0

作者：

Ionescu, Vlad Alexandru ^{[1
,2
]}

Gheorghe, Gina ^{[1
,2
]}

Adrian, Cosmin ^{[3
]}

Bebliuc, Alexandru ^{[4
]}

Pavelescu, Cezar ^{[4
]}

Enache, Valentin ^{[5
]}

Gheorghe, Florentina ^{[6
]}

Bacalbasa, Nicolae ^{[7
,8
]}

Diaconu, Camelia Cristina ^{[1
,2
,9
]}

机构：

[1] Univ Med & Pharm Carol Davila Bucharest, Fac Med, Bucharest 050474, Romania

[2] Clin Emergency Hosp Bucharest, Dept Internal Med, Bucharest 105402, Romania

[3] Clin Emergency Hosp Bucharest, Dept Radiol, Bucharest 105402, Romania

[4] Clin Emergency Hosp Bucharest, Dept Thorac Surg, Bucharest 105402, Romania

[5] Clin Emergency Hosp Bucharest, Dept Anat Pathol, Bucharest 105402, Romania

[6] Synevo Romania, Dept Biochem, Chiajna 077040, Romania

[7] Univ Med & Pharm Carol Davila Bucharest, Dept Surg, Bucharest 050474, Romania

[8] Fundeni Clin Inst, Ctr Excellence Translat Med, Dept Surg, Bucharest 022328, Romania

[9] Acad Romanian Scientists, Bucharest 050045, Romania

来源：

MEDICINA-LITHUANIA | 2024年 / 60卷 / 06期

关键词：

adenocarcinoma; typical carcinoid; aspergilloma; etiopathogenesis; diagnosis; prognosis; CARCINOID-TUMOR; ADENOCARCINOMA; CANCER; PROGNOSIS; PATIENT;

D O I：

10.3390/medicina60060953

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Several cases reported in the literature have confirmed the link between pulmonary aspergillosis and various malignant diseases. Furthermore, it has been observed that the correlation between carcinoid tumor and lung adenocarcinoma is quite uncommon. The etiopathogenic mechanisms underlying these correlations remain poorly defined. We present the case of a patient with three of these diseases: a lung adenocarcinoma with a lepidic pattern, a typical carcinoid, and pulmonary aspergillosis. An additional noteworthy aspect of this case pertains to the timely detection of both lung malignancies. Thus, the necessity for further investigation to ascertain the pathogenic connection among the three diseases is underscored. The ultimate objective is to enhance the prognosis of individuals diagnosed with lung cancer, which is a prevailing malignant disease on a global scale.

引用

页数：10

共 33 条

[1] Pulmonary Collision Tumor Consisting of Adenocarcinoma and Typical Carcinoid-A Case Report and Review of Literature [J].

Abbi, Kamal K. S. ;

Hameed, Muhammad K. ;

Jiang, Yuying ;

De Las Casas, Luis E. ;

Schwann, Thomas A. .

AMERICAN JOURNAL OF THERAPEUTICS, 2014, 21 (06) :E234-E238

[2] Long-term outcomes and prognostic factors of patients with surgically treated pulmonary carcinoid: our institutional experience with 104 patients [J].

Aydin, Ertan ;

Yazici, Ulku ;

Gulgosteren, Mahmut ;

Agackiran, Yetkin ;

Kaya, Sadi ;

Gulhan, Erkmen ;

Tastepe, Irfan ;

Karaoglanoglu, Nurettin .

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2011, 39 (04) :549-554

[3] Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids [J].

Caplin, M. E. ;

Baudin, E. ;

Ferolla, P. ;

Filosso, P. ;

Garcia-Yuste, M. ;

Lim, E. ;

Oberg, K. ;

Pelosi, G. ;

Perren, A. ;

Rossi, R. E. ;

Travis, W. D. .

ANNALS OF ONCOLOGY, 2015, 26 (08) :1604-1620

[4] Tumorlets in Familial History of Bronchopulmonary Carcinoid [J].

De Giorgi, Ugo ;

Fanini, Francesca ;

Amadori, Dino ;

Cancellieri, Alessandra ;

Fiorentini, Giammaria ;

Poletti, Venerino ;

Barzon, Luisa ;

Masi, Giulia .

JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (09) :1613-1614

[5] Tumorlets, Multicentric Carcinoids, Lymph-Nodal Metastases, and Long-Term Behavior in Bronchial Carcinoids [J].

Ferolla, Piero ;

Daddi, Niccolo ;

Urbani, Moira ;

Semeraro, Antonia ;

Ribacchi, Rodolfo ;

Giovenali, Paolo ;

Ascani, Stefano ;

De Angelis, Verena ;

Crino, Lucio ;

Puma, Francesco ;

Daddi, Giuliano .

JOURNAL OF THORACIC ONCOLOGY, 2009, 4 (03) :383-387

[6] Microallelotyping defines the monoclonal or the polyclonal origin of mixed and collision endocrine-exocrine tumors of the gut [J].

Furlan, D ;

Cerutti, R ;

Genasetti, A ;

Pelosi, G ;

Uccella, S ;

La Rosa, S ;

Capella, C .

LABORATORY INVESTIGATION, 2003, 83 (07) :963-971

[7]

Gheorghe G, 2020, ROM J MIL MED, V123, P213

[8] Neuroendocrine Tumors of the Lung: Current Challenges and Advances in the Diagnosis and Management of Well-Differentiated Disease [J].

Hendifar, Andrew E. ;

Marchevsky, Alberto M. ;

Tuli, Richard .

JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (03) :425-436

[9] Effect of patient immunodeficiencies on the diagnostic performance of serological assays to detect Aspergillus-specific antibodies in chronic pulmonary aspergillosis [J].

Hunter, Elizabeth Stucky ;

Wilopo, Bayu ;

Richardson, Malcolm D. ;

Kosmidis, Chris ;

Denning, David W. .

RESPIRATORY MEDICINE, 2021, 178

[10] Coexistence of carcinoid tumor and adenocarcinoma of the lung; morphological, immunohistochemical and genetic analyses, a case report [J].

Inoue, Chihiro ;

Konosu-Fukaya, Sachiko ;

Murakami, Kazuhiro ;

Saito-Koyama, Ryoko ;

Watanabe, Hirofumi ;

Mitomo, Hideki ;

Ishibashi, Naoya ;

Sugawara, Takafumi ;

Tabata, Toshiharu ;

Sasano, Hironobu ;

Nakamura, Yasuhiro .

DIAGNOSTIC PATHOLOGY, 2022, 17 (01)

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