Is the Central Sensitization Inventory (CSI) associated with quantitative sensory testing (QST)? A systematic review and meta-analysis

被引：11

作者：

Neblett, Randy ^{[1
]}

Sanabria-Mazo, Juan P. ^{[2
,3
,4
]}

Luciano, Juan V. ^{[2
,3
,5
]}

Mircic, Milica ^{[6
]}

Colovic, Petar ^{[7
]}

Bojanic, Marija ^{[7
]}

Jeremic-Knezevic, Milica ^{[6
]}

Aleksandric, Tijana ^{[6
,8
]}

Knezevic, Aleksandar ^{[6
,8
]}

机构：

[1] PRIDE Res Fdn, Dallas, TX 75235 USA

[2] Teaching Res & Innovat Unit, Parc Sanit St Joan Deu, St Boi De Llobregat, Spain

[3] Ctr Biomed Res Epidemiol & Publ Hlth CIBERESP, Madrid, Spain

[4] Autonomous Univ Barcelona, Dept Basic Dev & Educ Psychol, Cerdanyola Del Valles, Spain

[5] Autonomous Univ Barcelona, Dept Clin & Hlth Psychol, Fac Psychol, Cerdanyola Del Valles, Spain

[6] Univ Novi Sad, Fac Med, Novi Sad, Serbia

[7] Univ Novi Sad, Fac Philosophy, Dept Psychol, Novi Sad, Serbia

[8] Clin Ctr Vojvodina, Med Rehabil Clin, Novi Sad, Serbia

来源：

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | 2024年 / 161卷

关键词：

Pain; Nociplastic pain; Central Sensitization; Central Sensitization Inventory; Quantitative Sensory Testing; Systematic review; Meta; -analysis; Pain threshold testing; Pressure pain threshold; Conditioned pain modulation; Temporal summation; CONDITIONED PAIN MODULATION; WHIPLASH-ASSOCIATED DISORDERS; CROSS-CULTURAL ADAPTATION; TEST-RETEST RELIABILITY; PSYCHOMETRIC VALIDATION; DISCRIMINATIVE ABILITY; INDIVIDUAL-DIFFERENCES; TEMPORAL SUMMATION; WIDESPREAD PAIN; WIND-UP;

D O I：

10.1016/j.neubiorev.2024.105612

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Central sensitization (CS) involves an amplification of neural processing within the central nervous system that can result in widespread pain patterns and hypersensitivity to stimuli. The Central Sensitization Inventory (CSI) and various quantitative sensory testing (QST) methods purport to assess clinical markers of CS. The purpose of this systematic review and meta-analysis was to summarize and quantify the associations between total CSI scores and QST measures from previous studies. A systematic search identified 39 unique studies that were deemed eligible for the systematic review and 33 studies for meta-analyses (with 3314 subjects and 154 effect sizes), including five QST modalities: conditioned pain modulation, temporal summation, pressure pain threshold, heat pain threshold, and cold pain threshold. The meta-analysis yielded statistically significant CSIQST correlations in total subject samples for all five QST modalities. The strongest associations were identified between CSI scores and pain threshold testing, especially pressure pain threshold, in which 51% of effects sizes, from 29 studies and 3071 subjects, were determined to be in a medium to large range.

引用

页数：19

共 93 条

[1] Do "central sensitization" questionnaires reflect measures of nociceptive sensitization or psychological constructs? A systematic review and meta-analyses [J].