Neuromyelitis Optica Spectrum Disorders (NMOSDs) Diagnosed After Surgery for the Ossification of the Posterior Longitudinal Ligament of the Cervical and Thoracic Spine: A Case Report

被引:0
作者
Kodama, Hiroyasu [1 ]
Kawamura, Naohiro [1 ]
Nagatani, Satoshi [1 ]
Ishikawa, Yuki [1 ]
Kunogi, Junichi [1 ]
机构
[1] Japanese Red Cross Med Ctr, Dept Spine & Orthoped Surg, Tokyo, Japan
关键词
aqp4-antibody; nmosd; opll; surgery; diagnosis; MULTIPLE-SCLEROSIS; SPONDYLOTIC MYELOPATHY;
D O I
10.7759/cureus.61651
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Complications of compressive spinal cord myelopathy and demyelinating disease can be difficult to diagnose. A 65 -year -old woman gradually lost the ability to walk. Her imaging findings showed multiple spinal canal stenosis and ossification of the posterior longitudinal ligament in the cervical and thoracic spine. Some intramedullary signal changes were seen at sites distant from the spinal cord compression site. Although she underwent cervical and thoracic decompression and fusion surgery relatively early, her lowerextremity strength decreased after surgery. Her aquaporin 4 (AQP4)-antibody was found to be positive postoperatively, and she was diagnosed with NMOSD. Medical treatment for NMOSD improved her walking ability, and she finally became able to walk with a cane. In cases where there is a discrepancy between the site of strong stenosis and intramedullary signal changes, it is necessary to consider an anti-AQP4 antibody test and consultation with a neurologist.
引用
收藏
页数:9
相关论文
共 20 条
[1]   Cervical Ossification of the Posterior Longitudinal Ligament: A Computed Tomography-Based Epidemiological Study of 2917 Patients [J].
Bakhsh, Wajeeh ;
Saleh, Ahmed ;
Yokogawa, Noriaki ;
Gruber, Jillian ;
Rubery, Paul T. ;
Mesfin, Addisu .
GLOBAL SPINE JOURNAL, 2019, 9 (08) :820-825
[2]   Ossification of the posterior longitudinal ligament in the cervical spine: a review [J].
Boody, Barrett S. ;
Lendner, Mayan ;
Vaccaro, Alexander R. .
INTERNATIONAL ORTHOPAEDICS, 2019, 43 (04) :797-805
[3]   Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies [J].
Contentti, Edgar Carnero ;
Correale, Jorge .
JOURNAL OF NEUROINFLAMMATION, 2021, 18 (01)
[4]   Short Myelitis Lesions in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorders [J].
Flanagan, Eoin P. ;
Weinshenker, Brian G. ;
Krecke, Karl N. ;
Lennon, Vanda A. ;
Lucchinetti, Claudia F. ;
McKeon, Andrew ;
Wingerchuk, Dean M. ;
Shuster, Elizabeth A. ;
Jiao, Yujuan ;
Horta, Erika S. ;
Pittock, Sean J. .
JAMA NEUROLOGY, 2015, 72 (01) :81-87
[5]   The time course and phenotype of Uhthoff phenomenon following optic neuritis [J].
Fraser, Clare L. ;
Davagnanam, Indran ;
Radon, Mark ;
Plant, Gordon T. .
MULTIPLE SCLEROSIS JOURNAL, 2012, 18 (07) :1042-1044
[6]   Ossification of the Posterior Longitudinal Ligament: Pathophysiology, Diagnosis, and Management [J].
Le, Hai, V ;
Wick, Joseph B. ;
Van, Benjamin W. ;
Klineberg, Eric O. .
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2022, 30 (17) :820-830
[7]   Clinical outcomes following surgical management of coexistent cervical stenosis and multiple sclerosis: a cohort-controlled analysis [J].
Lubelski, Daniel ;
Abdullah, Kalil G. ;
Alvin, Matthew D. ;
Wang, Timothy Y. ;
Nowacki, Amy S. ;
Steinmetz, Michael P. ;
Ransohoff, Richard M. ;
Benzel, Edward C. ;
Mroz, Thomas E. .
SPINE JOURNAL, 2014, 14 (02) :331-337
[8]   Ossification of the Posterior Longitudinal Ligament of the Cervical Spine Etiology and Natural History [J].
Matsunaga, Shunji ;
Sakou, Takashi .
SPINE, 2012, 37 (05) :E309-E314
[9]   Cervical Spondylotic Myelopathy: A Guide to Diagnosis and Management [J].
McCormick, Johnathon R. ;
Sama, Andrew J. ;
Schiller, Nicholas C. ;
Butler, Alexander J. ;
Donnally, Chester J., III .
JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE, 2020, 33 (02) :303-313
[10]  
Meyer F, 1994, Zentralbl Neurochir, V55, P110