A review for non-antibiotic treatment of Helicobacter pylori: new insight

被引:5
作者
Shadvar, Neda [1 ,2 ,3 ]
Akrami, Sousan [4 ]
Sagharchi, Seyyed-Mohammad-Amin Mousavi [5 ]
Askandar, Rafee Habib [6 ]
Merati, Alireza [7 ]
Aghayari, Masoomeh [8 ]
Kaviani, Nikki [9 ]
Afkhami, Hamed [10 ,11 ]
Kashfi, Mojtaba [10 ,12 ]
机构
[1] Bushehr Univ Med Sci, Sch Med, Dept Microbiol & Parasitol, Bushehr, Iran
[2] Bushehr Univ Med Sci, Student Res Comm, Bushehr, Iran
[3] Bushehr Univ Med Sci, Persian Gulf Biomed Sci Res Inst, Persian Gulf Trop Med Res Ctr, Bushehr, Iran
[4] Univ Tehran Med Sci, Sch Med, Dept Microbiol, Tehran, Iran
[5] Islamic Azad Univ, Coll Basic Sci, Dept Microbiol, Shahr E Qods Branch, Tehran, Iran
[6] Sulaimani Polytech Univ, Res Ctr, Sulaymaniyah, Iraq
[7] Payame Noor Univ, Dept Psychol & Educ Sci, Tehran, Iran
[8] Islamic Azad Univ, Urmia Branch, Dept Microbiol, Fac Sci, Orumiyeh, Iran
[9] Kermanshah Univ Med Sci, Sch Med, Kermanshah, Iran
[10] Semnan Univ Med Sci, Nervous Syst Stem Cells Res Ctr, Semnan, Iran
[11] Shahed Univ, Fac Med, Dept Med Microbiol, Tehran, Iran
[12] Mashhad Univ Med Sci, Fellowship Clin Lab Sci, Mashhad, Iran
关键词
Helicobacter pylori (H. pylori); probiotic therapy; quadruple therapy; triple therapy; antibiotic; TRIMETHYLAMINE N-OXIDE; FERMENTED MILK; TRIPLE THERAPY; PEPTIC-ULCER; ERADICATION; METAANALYSIS; PREVALENCE; INFECTION; EXTRACT; ANTIBACTERIAL;
D O I
10.3389/fmicb.2024.1379209
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Gastric ulcers and gastric cancer are brought on by the Helicobacter pylori bacteria, which colonizes under the stomach mucous membrane. Different medication regimens are used to remove it, but the illness returns and becomes more resistant, which lowers the treatment rates. Additionally, this bacterium now exhibits a skyrocketing level of multi-drug resistance, necessitating recurrent therapeutic treatments. The negative effects of synthetic medications in comparison to conventional therapies are another significant factor in favor of non-pharmacological therapy. The most significant side effects of popular anti-gastric ulcer medications include nausea, vomiting, and diarrhea. Stomach ulcers have previously been treated with herbal remedies and complementary treatments like probiotics. When probiotics are ingested, the host experiences several advantages that may be brought about by altering the bacterial flora in the digestive system. Additionally, stronger-acting chemical compounds and plant extracts can be employed to treat patients. In this article, we look at the substances and medications that are utilized in place of synthetic stomach ulcer-curing treatments.
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页数:12
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