EXOSOMES AND THEIR APPLICATION AS DRUG DELIVERY SYSTEM IN CANCER THERAPY

被引：0
作者：
Yang, Kun [1 ,2 ]
Ma, Bingsuo [1 ,2 ]
Yu, Ting [1 ,2 ]
Li, Kexin [1 ,2 ]
Zhang, Liangming [1 ]
Yuan, Xiaoyan [1 ]
Zhang, Haizhu [2 ]
Yan, Zijun [1 ,3 ]
Chen, Tong [3 ]
机构：
[1] Panzhihua Cent Hosp, Dept Pharm, Panzhihua 617067, Sichuan, Peoples R China
[2] Dali Univ, Sch Pharm, Dali 671000, Yunnan, Peoples R China
[3] Kunming Med Univ, Sch Pharmaceut Sci, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China
来源：
ACTA POLONIAE PHARMACEUTICA | 2024年 / 81卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Exosomes; drug delivery system; cancer treatment; targeting; application; CELL-DERIVED EXOSOMES; EXTRACELLULAR VESICLES; ENGINEERING EXOSOMES; TARGETED DELIVERY; IN-VITRO; GROWTH; TUMOR; FUNCTIONALIZATION; NANOVESICLES; PACLITAXEL;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Exosomes are extracellular vesicles naturally released from cells. Exosomes from different sources play different roles in cellular component exchange, signal transduction, and pathological development. Exosomes have distinct biological characteristics such as low immunogenicity, easy uptake by cells, crossing the blood -brain barrier, natural targeting, and easy modification. Many studies show that exosomes as drug carriers have a great application prospect in cancer therapy. In this review, we review the biogenesis, origin, biological characteristics of exosomes, and the exosome drug delivery system and its application for cancer therapy are summarized to provide a reference for the study of exosomes.
引用
收藏
页码：13 / 33
页数：21
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