POPULATION EXPOSURE-RESPONSE ANALYSIS SUPPORTS EFFICACY OUTCOMES OF GARADACIMAB IN PATIENTS WITH HEREDITARY ANGIOEDEMA

被引：0
|
作者：
Sharma, A. [1 ]
Glassman, F. [1 ]
Garcia, R. [2 ]
French, J. [2 ]
Wiens, M. [2 ]
Miguel-Lillo, B. [1 ]
Lawo, J. [3 ]
Jacobs, I. [1 ]
Polhamus, D. [2 ]
Nandy, P. [1 ]
机构：
[1] CSL Behring, King Of Prussia, PA USA
[2] Metrum Res Grp, Tariffville, CT USA
[3] CSL Behring Innovat GmbH, Marburg, Germany
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2024年 / 115卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
PII-142
引用
收藏
页码：S95 / S95
页数：1
相关论文
共 50 条
  • [1] Population Pharmacokinetic/Pharmacodynamic and Exposure-Response Modeling of Garadacimab in Healthy Volunteers and Patients With Hereditary Angioedema
    Garcia, Ramon
    Cheng, Shen
    Glassman, Fiona
    Sharma, Ankur
    De Miguel-Lillo, Bernardo
    Wiens, Matthew
    Johnston, Curtis
    Lawo, John-Philip
    Pragst, Ingo
    French, Jonathan
    Polhamus, Dan
    Nandy, Partha
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2025,
  • [2] Population Pharmacokinetic/Pharmacodynamic Analysis Of Garadacimab, In Patients With Hereditary Angioedema
    Glassman, Fiona
    Sharma, Ankur
    Cheng, Shen
    Johnston, Curtis
    De Miguel Lillo, Bernardo
    Lawo, John-Philip
    Jacobs, Iris
    Polhamus, Daniel
    Nandy, Partha
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2024, 153 (02) : AB4 - AB4
  • [3] Exposure-Response Analyses of Lanadelumab in Patients with Hereditary Angioedema
    Wang, Yi
    Marier, Jean-Francois
    Kassir, Nastya
    Gosselin, Nathalie H.
    Martin, Patrick
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 143 (02) : AB41 - AB41
  • [4] Population PK and Exposure-Response Analyses of Icatibant in Pediatric Patients for the Treatment of Hereditary Angioedema
    Marier, J. F.
    Jomphe, Claudia
    Schranz, Jennifer
    Martin, Patrick
    Wang, Yi
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2016, 43 : S59 - S60
  • [5] Population Pharmacokinetics and Exposure-Response Analyses to Guide Dosing of Icatibant in Pediatric Patients With Hereditary Angioedema
    Wang, Yi
    Jomphe, Claudia
    Marier, Jean-Francois
    Martin, Patrick
    JOURNAL OF CLINICAL PHARMACOLOGY, 2021, 61 (04): : 555 - 564
  • [6] Pharmacokinetics, Pharmacodynamics, and Exposure-Response of Lanadelumab for Hereditary Angioedema
    Wang, Yi
    Marier, Jean-Francois
    Kassir, Nastya
    Chang, Colin
    Martin, Patrick
    CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2020, 13 (06): : 1208 - 1216
  • [7] PHARMACOMETRIC ANALYSIS SUPPORTS EARLY ONSET OF PROTECTION WITH GARADACIMAB AGAINST HEREDITARY ANGIOEDEMA ATTACKS
    Glassman, F.
    Sharma, A.
    Garcia, R.
    Lawo, J.
    Nenci, C.
    Pragst, I.
    Polhamus, D.
    Puchalski, T.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2024, 133 (06) : S32 - S32
  • [8] POPULATION PHARMACOKINETICS AND EXPOSURE-RESPONSE ANALYSES TO INFORM DOSING OF ICATIBANT IN PEDIATRIC PATIENTS WITH HEREDITARY ANGIOEDEMA.
    Wang, Y.
    Jomphe, C.
    Marier, J.
    Martin, P.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2020, 107 : S95 - S96
  • [9] Population Pharmacokinetics, Efficacy Exposure-Response Analysis
    Chan, Phyllis
    Yu, Jiajie
    Chinn, Leslie
    Prohn, Marita
    Huisman, Jan
    Matzuka, Brett
    Hanley, William
    Tuckwell, Katie
    Quartino, Angelica
    PHARMACEUTICAL RESEARCH, 2020, 37 (02)
  • [10] DONIDALORSEN EXPOSURE-RESPONSE ANALYSIS: HEREDITARY ANGIOEDEMA ATTACK RATE VERSUS PLASMA PREKALLIKREIN CONCENTRATION RELATIONSHIP
    Singh, P.
    Witjes, H.
    Kleijn, H.
    Diep, J.
    Bordone, L.
    Newman, K.
    Gao, X.
    ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2024, 133 (06) : S25 - S25
12345