The role of nitric oxide and hydrogen sulfide in spinal cord injury: an updated review

被引：0
|
作者：
Wen, Xiaoliang [1 ]
Ye, Yang [1 ]
Yu, Zhengquan [1 ]
Shen, Haitao [1 ]
Cui, Gang [1 ]
Chen, Gang [1 ]
机构：
[1] Soochow Univ, Affiliated Hosp 1, Dept Neurosurg, Brain & Nerve Res Lab, Suzhou, Jiangsu, Peoples R China
来源：
MEDICAL GAS RESEARCH | 2024年 / 14卷 / 03期
关键词：
central nervous system; excitotoxicity; hydrogen sulfide; ischemia/reperfusion injury; medical gas; nitric oxide; secondary injury; spinal cord injury; SECONDARY INJURY; OXIDATIVE STRESS; MECHANISMS; ISCHEMIA; REPERFUSION; APOPTOSIS; RECOVERY; CONTRIBUTES; ANTIOXIDANT; ASTROCYTES;
D O I：
10.4103/2045-9912.385946
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Medical gases play an important role in the pathophysiology of human diseases and have received extensive attention for their role in neuroprotection. Common pathological mechanisms of spinal cord injury include excitotoxicity, inflammation, cell death, glial scarring, blood-spinal cord barrier disruption, and ischemia/reperfusion injury. Nitric oxide and hydrogen sulfide are important gaseous signaling molecules in living organisms; their pathological role in spinal cord injury models has received more attention in recent years. This study reviews the possible mechanisms of spinal cord injury and the role of nitric oxide and hydrogen sulfide in spinal cord injury.
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收藏
页码：96 / 101
页数：6
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